GI Diseases Flashcards
Which of the following factors has not been implicated as an etiology of acute pancreatitis? A.Hypercalcemia B. Corticosteroids C. Trauma and surgery D. Hypertriglyceridemia E. Phenobarbitone in dogs F. L-aspariginase chemotherapy G. Septic shock H. Organophosphate in cats
B. Corticosteroids
What is the sensitivity of abdominal US in Dx acute pancreatitis in dogs? A. 5-15% B. 20-30% C. 55-70% D. 80-90%
55-70%
What statement regarding the accuracies (Sens & Spec)of pancreatic tests is correct? A. SPEC cPL >400 ng/mL is 90% specific B. The sensitivity of SNAP cPL is 87% for diagnosing mild or chronic pancreatitis C. Reduced GFR will cause false positive cPL D. cTLI is 80% sensitive for diagnosing spontaneous pancreatitis in dogs
A. SPEC cPL >400 ng/mL is 90% specific
Ultrasonographic changes of acute pancreatitis include all, except? A.Peripancreatic hyperechogenicity B. Pancreatic hyperechogenicity C. Duodenal corrugation D. Peritoneal anechoic fluid
B. Pancreatic hyperechogenicity
What is the most sensitive individual diagnostic test for acute pancreatitis in dogs? A. Abdominal radiograph B. Abdominal ultrasound C. Serum amylase activity D. Serum lipase activity E. cTLI F. cPL G Ultrasound guided FNA and cytology
F. cPL
A dog that has acute abdomen, elevated ALT and abnormal cPL (SNAP). Which is the correct statement/plan? A. You have made a diagnosis of acute pancreatitis as the cause of the acute abdomen B. Recommend and abdominal ultrasound C. Recommend abdominal contrast enhanced CT D. Additional assays like cTLI and urine Trypsin-alpha 1 protease inhibitor are indicated due to superior specificity
B. Recommend and abdominal ultrasound
What is the currently accepted diagnostic test in a dog with a high index of suspicion of pancreatitis? A. Amylase and lipase with cTLI B. Combination of abdominal US and cPL which is 84% sens and 75% specific C. Contrast enhanced abdominal CT D. Celiotomy with multiple biopsies
B. Combination of abdominal US and cPL which is 84% sens and 75% specific
Current EBM supports the diagnosis of specific therapy for acute pancreatitis. Which therapy in dogs is not specifically indicated? A. Crystalloid resuscitation B. Fentanyl CRI C. Broad spectrum antibiotics D. Maropitant, NK1 receptor antagonist
C. Broad spectrum antibiotics
Current feeding recommendations are enteral or PPN as soon as vomiting is under control or long-term dietary changes with dogs that have dyslipidemia. What diet should be fed? A. I/D B. Z/D C. Selected Protein D. Intestinal Low fat
D. Intestinal Low fat
What is the most common clinical sign in cats with pancreatitis? A. Vomiting and diarrhea B. Abdominal pain C. Anorexia and lethargy D. Icterus
C. Anorexia and lethargy
What is reported as an important prognosticators in cats that present with acute pancreatitis? A. BCS, overweight cats have more severe pancreatitis B. Age, older cats do poorly C. Hyperkalemia & hypoCa with hypothermia D. Left shift neutrophilia
C. Hyperkalemia & hypoCa with hypothermia
Which statement regarding pancreatitis is true? A.The most common form of pancreatitis in dogs is acute B. The most common form of pancreatitis in cats is acute C. The most common form of pancreatitis in dogs and cats is chronic, or chronic active D. Obesity is a predisposing factor for AP and is associated with worse pancreatitis in both dogs and cats E. High fat diets/dietary indiscretion can cause pancreatitis in both dogs and cats F. Vomiting and abdominal pain are hallmark clinical signs in both dogs and cats
C. The most common form of pancreatitis in dogs and cats is chronic, or chronic active
Which statement regarding the diagnostic accuracies of tests for pancreatitis in cats is correct? A. Radiography is highly sensitive and specific in pancreatitis B. Abdominal ultrasound is insensitive (23% agreement with necropsy), but fairly specific as in peripancreatic hyperechogenicity being diagnostic C. fTLI has a long half-life and a sensitivity of 80% fPL is extremely sens. in mild acute pancreatitis and chronic pancreatitis D. Serum amylase and lipase are at least 70-80% sensitive in the diagnosis of pancreatitis
B. Abdominal ultrasound is insensitive (23% agreement with necropsy), but fairly specific as in peripancreatic hyperechogenicity being diagnostic
Which is not a complication of chronic active pancreatitis in dogs? A. EPI B. Pseudocyst C. Pancreatic abscess D. Diabetes mellitus E. Pancreatic bladder
E. Pancreatic bladder
Bobby is referred to your clinic for further investigation of liver disease. He is weak, with non-specific signs of pain. Biochemistry shows, ALT (2 x TN), AST (4 x TN). What should you also test? A. Liver enzymes: ALKP, GGT, Abdominal US B. Muscle enzymes: CK, LDH; EMG and Toxo titres, 2M Ab assay
B. Muscle enzymes: CK, LDH; EMG and Toxo titres, 2M Ab assay
Maggie, a 6 year old, FS Shih tsu, visits your practice for a routine health screen. She has been diagnosed with idiopathic epilepsy and is on phenobarb. She is otherwise healthy. Biochemistry detects 10 x TN ALKP, 8 x TN ALT.Which is the correct statement? A. This is enzyme induction from phenobarbitone B. The liver enzymes are prognostic of phenobarb damage C. Recommend liver function testing and US/biopsy D. Immediately discontinue the phenobarb
C. Recommend liver function testing and US/biopsy
Mable, a 6 year old, FS Labrador retriever visits your practice for a routine health screen. She is otherwise healthy. Biochemistry detects 2 x TN ALT.What do you recommend to the owner? A. This is a mild increase, nothing to worry about as it does not indicate dysfunction B. Recheck in 3-5 days, ensure it decreases by 50% C. Start on SAMe, Ursodiol liver supplements D. Recommend liver function testing E. Recommend abdominal ultrasound
All but A! B. Recheck in 3-5 days, ensure it decreases by 50% C. Start on SAMe, Ursodiol liver supplements D. Recommend liver function testing E. Recommend abdominal ultrasound
“Silkworm”, a 2 year old overweight, MN, DSH is presented to your clinic for anorexia. Biochemistry tests detect 2 x TN ALKP.Which interpretation is correct? A. ALKP has many isoenzymes. This is not liver specific B. ALKP is liver specific for the cat and “Silkworm” has hepatic lipidosis C. Increased ALKP is not significant, due to the long half life and it is ‘too sensitive
B. ALKP is liver specific for the cat and “Silkworm” has hepatic lipidosis
“Quinn”, a 2 year, MN, Cockapoo in ICU is being treated for onion toxicity and has received a blood transfusion for anemia. He is now icteric.Which statement is correct regarding liver function? A. A bile acid stim. test is indicated to confirm liver dysfunction B. An abdominal US excluding EHBO is sufficient to confirm liver dysfunction C. There is no liver dysfunction, this is all pre-hepatic hemolysis
B. An abdominal US excluding EHBO is sufficient to confirm liver dysfunction
You are managing a 6 month old Yorkshire terrier with neurological signs, microcytosis and ammonium biurate crystalluria. How would you investigate for PSS? A. Ammonia tolerance test B. Bile acid stim C. Urea, Alb, Gluc D. Liver biopsy
B. Bile acid stim