GI A&P - hormones Flashcards

1
Q

mucous neck cell secretes…

A

thin, watery mucus

bicarb

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2
Q

parietal cells secrete…

A
gastric acid (HCl)
intrinsic factor (Ca2+ absorption)
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3
Q

enterochromaffin-like cells secrete…

A

histamine

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4
Q

histamine hormone does what

A

stimulates the parietal cells to secrete HCl- acid

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5
Q

chief cells secrete…

A

pepsinogen

gastric lipase

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6
Q

D cells secrete…

A

somatostatin

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7
Q

somatostatin does what

A

inhibits secretion of gastrin by G cells

inhibition of gastrin results in inhibition of histamine release from ECL cells and parietal cell release of HCl-

ultimately: inhibits release of gastrin, histamine, and HCl- acid

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8
Q

G cells secrete…

A

gastrin to stimulate acid production in response to eating

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9
Q

ACh of the enteric nervous system does…

A

contraction of smooth muscle in GI wall

relaxes sphincters

increases salivary secretion
increases gastric secretion
increases pancreatic secretion

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10
Q

NE of the enteric nervous system does…

A

relaxation of smooth muscle in GI wall

contraction of sphincters

increases salivary secretion

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11
Q

vasoactive intestinal peptide (VIP) of the enteric nervous system does…

A

relaxes smooth muscle in GI wall

increases intestinal secretion
increases pancreatic secretion

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12
Q

substance P of the enteric nervous system does…

A

increases contraction of the smooth muscle in GI wall

increases salivary secretion

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13
Q

neuropeptide P of the enteric nervous system does…

A

relaxes smooth muscle in GI wall

decreases salivary secretion

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14
Q

amylase

A

breaks down polysaccharides to mono or disaccharides

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15
Q

lysozyme

A

enzymes that kill bacteria

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16
Q

secretin of the duodenum does…

A

decreases gastric emptying

17
Q

CCK of the duodenum

A

decreases gastric emptying due to presence of fats in chyme

18
Q

oxyntic glands are made up of cells that secrete hormones that…

A

increase motility, absorption, and digestion

19
Q

pyloric glands are made up of cells that secrete hormones that…

A

slow down digestion, absorption, and motility

20
Q

gastrin hormone

A

stimulates H+ secretion by the parietal cells and growth of the gastric mucosa

21
Q

pepsinogen activity…

A

is converted into active enzyme pepsin through clevage with HCl-

pepsin then cleaves more pepsinogen into pepsin

pepsin breaks down ingested proteins into smaller fragments and AA

22
Q

gastric mucus contains…

also inhibits…

A

bicarb to neutralize HCl- acid

inhibits pepsin to prevent autodigestion

23
Q

lipase

A

breaks down fats

24
Q

proteases

A

breaks down proteins

25
pancreatic juices contains... and functions to...
Contains electrolytes, bicarbs, digestive enzymes that neutralizes gastric acid and provides a basic environment for pancreatic enzymes
26
pancreatic juices are stimulated for release by...
gastric acid CCK from duodenum Vagal stimulation
27
insulin
responds to increased blood glucose and is released from the beta cells of the islets of Langerhans of the pancreas
28
glucagon
is released in response to low blood glucose and stimulates the liver to metabolize glycogen into glucose and release into the blood
29
secretin
major stimulating factor in production of pancreatic juices released from S cells of the duodenum in response to an increased pH in the duodenum
30
S cells of duodenum
secrete secretin to act on pancreas to cause a pancreatic secretion of a watery substance rich in bicarb
31
I cells of duodenum
secrete CCK to act on pancreas to cause the pancreas to secrete a substance rich in digestive enzymes