GI A&P - hormones Flashcards
mucous neck cell secretes…
thin, watery mucus
bicarb
parietal cells secrete…
gastric acid (HCl) intrinsic factor (Ca2+ absorption)
enterochromaffin-like cells secrete…
histamine
histamine hormone does what
stimulates the parietal cells to secrete HCl- acid
chief cells secrete…
pepsinogen
gastric lipase
D cells secrete…
somatostatin
somatostatin does what
inhibits secretion of gastrin by G cells
inhibition of gastrin results in inhibition of histamine release from ECL cells and parietal cell release of HCl-
ultimately: inhibits release of gastrin, histamine, and HCl- acid
G cells secrete…
gastrin to stimulate acid production in response to eating
ACh of the enteric nervous system does…
contraction of smooth muscle in GI wall
relaxes sphincters
increases salivary secretion
increases gastric secretion
increases pancreatic secretion
NE of the enteric nervous system does…
relaxation of smooth muscle in GI wall
contraction of sphincters
increases salivary secretion
vasoactive intestinal peptide (VIP) of the enteric nervous system does…
relaxes smooth muscle in GI wall
increases intestinal secretion
increases pancreatic secretion
substance P of the enteric nervous system does…
increases contraction of the smooth muscle in GI wall
increases salivary secretion
neuropeptide P of the enteric nervous system does…
relaxes smooth muscle in GI wall
decreases salivary secretion
amylase
breaks down polysaccharides to mono or disaccharides
lysozyme
enzymes that kill bacteria
secretin of the duodenum does…
decreases gastric emptying
CCK of the duodenum
decreases gastric emptying due to presence of fats in chyme
oxyntic glands are made up of cells that secrete hormones that…
increase motility, absorption, and digestion
pyloric glands are made up of cells that secrete hormones that…
slow down digestion, absorption, and motility
gastrin hormone
stimulates H+ secretion by the parietal cells and growth of the gastric mucosa
pepsinogen activity…
is converted into active enzyme pepsin through clevage with HCl-
pepsin then cleaves more pepsinogen into pepsin
pepsin breaks down ingested proteins into smaller fragments and AA
gastric mucus contains…
also inhibits…
bicarb to neutralize HCl- acid
inhibits pepsin to prevent autodigestion
lipase
breaks down fats
proteases
breaks down proteins