GI Flashcards
What type of drug is Omeprazole
PPI (Proton Pump Inhibitor)
What is the mechanism of action of Omeprazole
Inhibits the ATPase proton pump on parietal cells
where H+ ions are pumped out into the lumen.
What is Omeprazole used to treat?
Peptic Ulcers
Chronic Pancreatitis
What class of drugs are Amoxycillin, Clarithromycin, Metronidazole
Antibiotics
What is the mechanism of action of Amoxycillin, Clarithromycin, Metronidazole
Fight against bacteria (H. Pylori) in peptic ulcers
What is Amoxycillin, Clarithromycin, Metronidazole used to treat?
Peptic Ulcers
What are the side effects of Amoxycillin, Clarithromycin, Metronidazole use?
Antibiotic resistance.
What type of drug is Propranolol?
Beta-Blockers
What is the mechanism of action of Propranolol
Used in portal hypertension, prophylactically of a variceal haemorrhage
What is Propranolol used to treat?
Portal Hypertension (Prevention of Varices)
What class of drug is Terlipressin
Vasoactive Drugs
What is the mechanism of action of Terlipressin
Used in portal hypertension to cause
vasoconstriction of varices and prevent further
bleeding
What is Terlipressin used to treat?
Portal Hypertension (Prevention of Varices)
What is phlebotomy used to treat?
Hereditary Haemochromatosis
What is the mechanism of action of phlebotomy
Repeated Phlebotomy (removal of blood via venesection). 500mL until haemocrit falls below 37%, then maintenance 500mL every 2-3 months