GI Flashcards
Most common environmental factor assoc with pancreatic cancer?
Smoking
Courvoisier Sign
D/t?
Obstruction causing the gallbladder to become palpable
Often malignant neoplasm obstructing CBD
Pathogen responsible for most hepatic abscess
Klebsiella pneumoniae. (Also associate with infections of biliary tract, fatty liver disease, and DM pts.)
Gastritis
gnawing epigastric pain, anemia, extremity paresthesia
GERD
persistent hoarseness, dry cough, dysphagia
Gastric ulcer
Left sided chest pain and anorexia
Esophagitis
Severe chest pain, nausea, bitter “water brash”
Duodenal ulcer
Abdominal pain, dyspepsia, weight gain
Glycogen Storage Disorder I (Von Gierke’s disease)
Auto Rec deficiency in Glucose 6 Phosphatase
Doll Like Face
hypoglycemia when fasting –> lactic acidosis and Kussmaul resps
Tx: cornstarch feedings
What is the best test to evaluate biliary dilatation without gallstones on US?
CT of abd with contrast
What electrolyte abnormality is the hallmark of Refeeding syndrome?
HyPOPhosphatemia
Most effective treatment for Non-Alcoholic Steatohepatitis
Weight loss
Zenker’s diverticulum is due to what?
motor dysfunction of cricopharyngeus allowing for herniation between its muscle fibers
What are the surgical indications for diverticulitis?
Tx?
Presence of a fistula
perforation
2+ attacks in the same region
Tx: Partial colectomy
What is a common cause of GI blood loss (manifesting as iron deficiency anemia) in elderly patients who have no other obvious source of bleeding?
Angiodysplasia
What should you always do for a new onset dysphagia?
Upper endoscopy
Booerhaave v. Mallory Weiss
Boerhaave is esophageal perforation after excessive vomiting/bulimia
Mallory Weiss is superficial mucosal tear seen in a weekend warrior
Dx. Boerhaave syndrome?
Gastrograffin swallow then Barium then EGD
Dx. Mallory Weiss?
EGD
Tx. Diffuse esophageal spasm?
CCB, Nitrates
Dx. for achalsia and zenker’s diverticulum?
barium swallow
Schatski’s ring keywords
steakhouse dysphagia
barium swallow
surgery to lyse ring
Gold standard for confirming reflux?
24 hr esophageal pH monitoring
Barret’s Esophagus has a risk of developing what ca?
Adenocarcinoma
Ulcer types Curling v. Cushing
“burn from curling iron”
“cushion the brain”
Gastric ca. keywords
Mucosal cell metaplasia
Signet ring cells
Virchow’s (left supraclavicular) node
Most common location of a VIPoma? Keywords?
@ pancreatic tail
tea-colored watery diarrhea
hypOkalemia, hypochlorhydria
Right sided colon ca. keywords
Bleed –> Iron Def. anemia
+ Melena
Left sided colon ca. keywords
Apple core
Obstructing
Pencil stool
Hematochezia
Angiodysplasia of colon is associated with?
Aortic Stenosis
Heyde’s syndrome
If there’s Upper GI Bleed, what’s the next dx. step?
EGD if stable
NG tube and lavage
If there’s Lower GI Bleed with no bleeding, what’s the next dx. step?
Colonoscopy
If there’s Lower GI Bleed with medium amount of bleeding, what’s the next dx. step?
Tagged RBC scan
If there’s Lower GI Bleed with high bleeding, what’s the next dx. step?
Arteriogram
Labs in Biliary Tract obstruction
Increased ALKPHOS, GGT, Conjugated Bili
Jaundice, pruritus, clay stool, dark urine
Ulcerative Colitis keywords
Bloody diarrhea Colon ca. (do annual colonoscopy after 8 yrs of disease) Crypt Abscesses Erythema nodosum Lead Pipe Mucosa and submucosa inflamm. Primary Sclerosing cholangitis (pANCA, ANA) Pseudopolyps @ Rectum Toxic Megacolon
Tx: 5ASA, Steroids
Crohns keywords
Anti-Saccharomyces-Cervisiae Abs (ASCA) Cobblestone Fistulas Non-caseating granulomas Perianal fissures Skip lesions Transmural Watery diarrhea Nephrolithiasis (IBD causes impaired fat absorption)
Tx: 5ASA, Corticosteroids, Infliximab IV (TNFa Ab), No NSAIDS.
Primary Sclerosing Cholangitis (PSC) keywords
HLA-DR52A pANCA Males with Ulcerative Colitis Cholangiocarcinoma risk Onion Skinning
Tx: Ursodiol, ERCP, Liver transplant
Most common type of colonic polyps?
Adenomatous. Have malignant potential.
Primary Biliary Cirrhosis (PBC) –> cholestasis
S&S
Dx
Tx
middle age woman
pruritus, skin hyperpigmentation,
hepatomegaly, fatigue, xanthelasma, steatorrhea
Increased ALKPHOS
+ Anti-mitochondrial Ab (AMA)
Tx: Ursodeoxycholic Acid
Esophageal Varices Ppx?
Propranolol, Nadolol (non-selective BBs)