Derm Flashcards
Psoriasis keywords
Extensors
Onycholysis
Auspitz
Munro’s microabscess (Neutrophils in stratum corneum)
What is onycholysis and what disease process are you likely to see it in?
Separation of nail from nail bed (white area of nail plate getting bigger)
Erythema Multiforme description
Triggers
Complications
Diagnostic considerations
Erythematous Targetoid lesions on mucous membranes, palms, soles
Triggered by HSV, PCN, Sulfa, NSAIDS
!TEN/SJS
Do an RPR to r/o syphilis
Steven Johnson Syndrome (SJS) keywords
Basal cell degeneration
Toxic Epidermal Necrolysis (TEN) keywords
Epidermal Eosinophils
>30%
Erythema Nodosum description
Triggers
Diagnostic considerations
Painful erythematous lower leg nodules
Triggered by Strep, Coccidiodes, TB, Sulfa, Sarcoid, Crohn’s UC, Behcet’s
Rule out the triggers above (ASO, PPD, CXR for sarcoid, Bowel series). May see False +VDRL
Bullous Pemphigoid keywords
IgG + C3 anti-Hemidesmosomes on basement membrane
Tense
Prednisone tx.
Pemphigus Vulgaris (vulgar=bad)
IgG Anti-Desmosomes Flaccid \+ Nikolsky Tombstoning Prednisone + IVIg, MMF, Rituximab, AZA, MTX tx.
Genital Warts keywords
HPV 16 and 18
Tx: Freezing, Podophyllin, Trichloroacetic acid, Imiquimod, 5FU
Scarlet Fever keywords
Strep pyogenes
sunburn + goosebumps
strawberry tongue
Tx. PCN
Salmonella Typhi keywords
Pink rose spots on trunk
Tx. Fluoroquinolones and Ceftriaxone
Ludwig’s angina
Cellulitis of submental/maxillary/lingual space from infected tooth
Most common causes of necrotizing fasciitis
Medical tx.
Strep pyogenes (10%) Staph aureus + E. coli + Clostridium perfringens
PCN, Clindamycin, Metronidazole/Ceftriaxone
Fournier gangrene
genital and perineal necrotizing fasciitis
Isoretinoin
Indications
Complications
for severe cystic acne
teratogenic, ^ LFTs, ^ chol, ^ TGs, worsen depression