Derm Flashcards

1
Q

Psoriasis keywords

A

Extensors
Onycholysis
Auspitz
Munro’s microabscess (Neutrophils in stratum corneum)

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2
Q

What is onycholysis and what disease process are you likely to see it in?

A

Separation of nail from nail bed (white area of nail plate getting bigger)

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3
Q

Erythema Multiforme description
Triggers
Complications
Diagnostic considerations

A

Erythematous Targetoid lesions on mucous membranes, palms, soles
Triggered by HSV, PCN, Sulfa, NSAIDS
!TEN/SJS
Do an RPR to r/o syphilis

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4
Q

Steven Johnson Syndrome (SJS) keywords

A

Basal cell degeneration

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5
Q

Toxic Epidermal Necrolysis (TEN) keywords

A

Epidermal Eosinophils

>30%

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6
Q

Erythema Nodosum description
Triggers
Diagnostic considerations

A

Painful erythematous lower leg nodules
Triggered by Strep, Coccidiodes, TB, Sulfa, Sarcoid, Crohn’s UC, Behcet’s
Rule out the triggers above (ASO, PPD, CXR for sarcoid, Bowel series). May see False +VDRL

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7
Q

Bullous Pemphigoid keywords

A

IgG + C3 anti-Hemidesmosomes on basement membrane
Tense
Prednisone tx.

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8
Q

Pemphigus Vulgaris (vulgar=bad)

A
IgG Anti-Desmosomes
Flaccid
\+ Nikolsky
Tombstoning
Prednisone + IVIg, MMF, Rituximab, AZA, MTX tx.
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9
Q

Genital Warts keywords

A

HPV 16 and 18

Tx: Freezing, Podophyllin, Trichloroacetic acid, Imiquimod, 5FU

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10
Q

Scarlet Fever keywords

A

Strep pyogenes
sunburn + goosebumps
strawberry tongue
Tx. PCN

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11
Q

Salmonella Typhi keywords

A

Pink rose spots on trunk

Tx. Fluoroquinolones and Ceftriaxone

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12
Q

Ludwig’s angina

A

Cellulitis of submental/maxillary/lingual space from infected tooth

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13
Q

Most common causes of necrotizing fasciitis

Medical tx.

A
Strep pyogenes (10%)
Staph aureus + E. coli + Clostridium perfringens

PCN, Clindamycin, Metronidazole/Ceftriaxone

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14
Q

Fournier gangrene

A

genital and perineal necrotizing fasciitis

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15
Q

Isoretinoin
Indications
Complications

A

for severe cystic acne

teratogenic, ^ LFTs, ^ chol, ^ TGs, worsen depression

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16
Q

Most likely side effect of Transretinoin

A

excessive dryness and skin peeling

17
Q

Tinea Versicolor description
Pathogen
Tx

A

HyPO/HyPER-pigmented scaly patches “spaghetti and meatballs”
Malassezia furfur/Pityrosporum orbiculare

Ketoconazole 2% or Selenium Sulfide topical

18
Q

Scabies keywords

Tx

A

night time post-shower pruritus
linear pimples betwen knuckles, axilla

5% Permethrin from the neck down for pts. AND partners

19
Q

Rosacea keywords

Tx

A

facial erythema + telangiectasias

Metronidazole

20
Q

What is actinic keratosis a precursor of?

Tx?

A

SCC

Topical 5FU

21
Q

Basal Cell ca. keywords

A

upper face (above the lip)
UV sun exposure
palisading outer layer

22
Q

SCC keywords

A

sun exposure (below the lip)
keratin pearls
heaped up margins

23
Q
Mycosis Fungoides (Cutaneous T-cell Lymphoma)
Tx
A

Cerebriform lymphocytes/Sezary cells

Phototherapy

24
Q

Leprosy keywords

Pathogen

A

Carbol fuchsin stian
Peripheral n. damage

Mycobacterium Leprae (G+R, acid fast)

25
Q

Vasospastic ulcers

A

small, dry, painful, no pulses d/t vasospastic process like Raynaud’s

26
Q

Venous insufficiency ulcers most common location

A

medial malleolus

27
Q

Livedo reticularis is generally a symptom of what disease?

A

Cholesterol embolization

28
Q

What would you see in the eyes of someone with cholesterol embolization?

A

Hollenhorst plaques in retinal a.’s

29
Q

Melanocytes are derived from what kind of cells? What is a marker for melanoma?

A

Neural crest cells

S100

30
Q

Most common AE of oral Tetracyclines (Minocycline)

A

Photosensitivity

Tetracyclines are contraindicated in pregnancy d/t risk of abnormal fetal bone development and tooth discoloration.

31
Q

Vitiligo

d/t

dx

tx

A

Autoimmune melanocyte destruction

May be assoc. with other autoimmune disorders (thyroid disease, DM) so
Dx: check TSH and Fasting Blood Glucose

Tx: phototherapy, laser therapy

32
Q

Trichophyton dermatophyte keywords

A

well circumscribed
scaly and pruritic lesions

Tx: Ketoconazole, Terbinafine, Miconazole