Gestational Trophoblastic Diseases Flashcards
1
Q
GESTATIONAL TROPHOBLASTIC TUMOURS
Invasive mole
A
Invasive mole is a hydatidiform mole that has invaded the myometrium or adjacent structures.
It occurs in 20% of patients who have undergone evacuation of a molar pregnancy.
Microscopic findings are similar to that of a hydatidiform mole. It may regress spontaneously or completely penetrate the uterus and cause haemoperitoneum.
2
Q
GESTATIONAL TROPHOBLASTIC TUMOURS
Persistent mole
A
20-30% of cases after a complete mole
4-5% of cases after incomplete mole
Diagnosis; on re-elevation or persistent plateau of hCG for at least 3 consecutive weeks
RISK FACTORS
Older age
Previous molar pregnancy
features of marked trophoblastic overgrowth
3
Q
Features of Hyatidiform Mole
A
- Mass of vesicles
- Loss of fetal blood vessels
- Hyperplasia of the trophoblast
4
Q
Diagnosis of Hydatidiform Mole
A
- From clinical presentation: the passage of vesicles
- hCG levels in excess of 100,000mIU/ml
- Ultrasound scan showing a ‘snowstorm’ appearance
