Gerontologic Alterations Flashcards
lipofuscin
wear and tear pigment
yellow and brown
keratoses
premalignant lesions
aging effects on the peripheral vascular system includes
rise in SBP until age 80
what blood pressure is generally unaffected by age or decreases
diastolic
older adults generally have contracted intravascular volumes and impaired baroreflexes which may be exacerbated by
diuretics
sodium and water depletion
* leads to orthostatic hypotension
changes in chest wall compliance lead to
greater contribution to breathing from the diaphragm and abdominal muscles
typical PaCo2 for healthy people older than 65 years is about
89
control of ventilatory responses to what fall by 50 and 40% respectively in the older adult
hypoxia and hypercapnia
between the ages 25 and 85 approximately 40% if nephron’s become sclerotic and others hypertrophy. what is sclerosis and what does it mean for renal blood flow
accompanied by atrophy of afferent and efferent arterioles leading to fall in renal blood flow
the most important age related change in liver function is
decreased capacity to metabolize medications
what is cited as common cause of adverse medication reactions in older adult population
polypharmacy
older adults with major infections will have a normal white count but
differential count usually shows a large proportion of immature forms
liver and kidneys are they able to metabolize and excrete medications
no
cause of the changes in liver and kidney what happen to med rates
changes in absorption, time to peak, plasma concentration, clearance