Endocrine Flashcards
A1C goal value for diabetics
under 7
A1c is the average of
3 moths
normal value of A1C
4-6
cortisol increases
glucose
what does insulin do
promote glucose uptake by target cells and glucose storage as glycogen; presents fat and glycogen breakdown, inhibits gluconeogensis, increases protein synthesis
3 P
polyuria
polydipsia
polyphasic
type 1 onset
rapidty
type 2 onset
over time
Lantus duration
20-26 hours
Novolog onset
15 mins
metformin
diarrhea and ct contrast
sick day rules
patients should not stop taking their insulin or oral agent
check blood sugar every 3-4 hours
modify diet to include and check ketones
notify care provider if not tolerating diet or becoming dehydrated
DKA causes
infection, surgery, trauma
inadequate insulin malfunctioning insulin pump, management changes
pregnancy and growth spurts
emotional stress
drugs-steroids and epi norepinephrine
DKA
hyperglycemia, ketosis
metabolic acid
DKA glucose level
> 250
DKA pH
less than 7.3
DKA other issues
dehydration
electrolytes
DKA electrolyte
K
ABG DKA
met acid
- compensation resp ak
when should we change IV to dextrose
BS around 200-250
DKA adminsiter
K
how often glucose
1hr
how often electrolytes
4 hours
first indication of ICP
change in LOC
hypoglycemia onset
rapid
DKA other signs
fruit breath
hypotension
tachy
kussmaul
hypoglycemia oral
1/2 cup juice with starch and protein
hypoglycemia if unconsious
1 am D50
- half life only 30 min
HHS glucose
greater than 600
arterial pH HHS
greater than 7.3 (normal)
serum osmo HHS
over 320
ketonuria HHS
absent or mild
HHS mainfestations
profound thirst
HHS treatment
rehydration
insulin
electrolyte
- potassium
hypoglycemia NPO
amp of d50
ADH normal value
1-5
urine and blood osmo serum normal
275-295
pituitary secretes
ADH
DI does what to ADH
decrease
DI hydration
extracellular dehydration
DI salt
hypernatremia
DI BP
hypotensive
- hypovolemic shock
DI urine output
> 300
serum osmolality DI
> 300 (high)
synthetic vasopressin
demopressin
SIADH ADH level
too much
SIADH salt
hyponatremia
SIADH can be caused by
cancer or head injury
SIADH urine osmo
increased
urine output SIADH
below
SIADH fluid
hypertonic (3)
SIADH and DI serum osmo
SIADH decrease
DI increases
SIADH and DI urine osmo
SIADH increase
DI decrease
hypothyroidism levels
high TSH
low T4
hyperthyroidism levels
low TSH
high T4
thyroid storm is
hyperthyroidism
thyroid storm
- thermo
fever
thyroid storm
- heart
a fib
thyroid storm
- CNS
agitation,
restless
delirium
thyroid storm lab findings
TSH bery low
T3 and T4 high
graves disease
hyperthyroidism
goiter
opthamopathy
severe hypothyroidism leads to
coma (myxedema coma)
Addisons disase
adrenal cortical insuff
bushings sundrome
excessive cortisol
pheochromocytoma
tumor of adrenal medulla
- must remove tumor