Geriatrics

Question 1

Side effect of Donepezil

Answer 1

Insomnia
Relatively Contraindicated in Bradycardia

Antipsychotics are associated with a significant increase in mortality in dementia patients

Question 2

Vascular Dementia Treatment

Answer 2

Control Vascular Risk Factors

Only consider AchE inhibitors OR Memantine if Comorbidity with Parkinson’s, LWBD or Alziemers

Question 3

MMSE Scores

Answer 3

Mild = 21-26
Moderate = 10-20
Severe = <10

<24 is indicative of Dementia

Question 4

Waterlow Score

Answer 4

Grade 1
Grade 2 - Partial Thickness Loss (E+D)
Grade 3 - Full Thickness Loss
Grade 4 -

Question 5

APOE Allele Associated with Alziemers

Answer 5

Apoprotein E allele E4 - encodes a cholesterol transport protein

Autosomal Dominant
Amyloid precursor protein (chromosome 21) Presenilin 1 (chromosome 14)
Presenilin 2 (chromosome 1)

Tau is a protein that interacts with tubulin to stabilize microtubules and promote tubulin assembly into microtubules