Genomes Flashcards

1
Q

What is a genome?

A

is sum of the genetic material contained within the an organism

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2
Q

kilobase, megabase, Gigabase

A

1000, 1million, 1billion

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3
Q

What DNA is present in a prokaryotic? what DNA is present in a eukaryotic cell?

A
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4
Q

Talk about the sum of genetic material in Viruses, Prokaryotic, Eukaryotic

A

Single or double stranded, Chromosomes, + Plasmid , Plant: Nucleus + Chloroplast + mitochondria , Nucleus + mitochondria

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5
Q

Do cells contain multiple mitochondria

A

Yes

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6
Q

Talk about chloroplast and mitochondria

A

Genomes are circular, and have double membranes.

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7
Q

Are their more copies of mitochondrial genome or nuclear genome in most cells.

A

Easier because their is more copies. The more energy the more than one cell can produce

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8
Q

What is a complete genome sequence? why are they not if so?

A

An attempt to sequence the base pair sequence of all of the DNA in an organism. Because of scaffolds contain gaps, repetitive- skips. Heterochromatin difficult to sequence , usually missing from “whole” genome sequence

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9
Q

Are virus genomes small?

A

Yes

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10
Q

Are genome size and the amount of protein coding DNA linear

A

No, genomes can increase in size and the percentage of proteins coding sequences decreases especially in eukaryotes

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11
Q

What factors do you think lead a linage genome to expand or contract

A

The environment, polyploidy or mutations

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12
Q

Why do prokaryotes tend to be compact?

A

The genes are mostly in operons and most of the genome is protein coding genes.

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13
Q

Why are Eukaryotes usually larger

A

Because of the functions and structures related to gene regulation

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14
Q

Eurkayotes are comprised of diverse array of elements but…

A

only some are translated.

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15
Q

Constant transcription to meet demand because you need ribosomes

A

because you need ribosomes for RNA genes being repetitive sequences

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16
Q

What are centromeres and do Eurkayotes include that? What else does it inculde?

A

Dense packed regions, Yes and tele more

17
Q

Why sequence a genome

A

For the function so mutation doesn’t happen or to track it

18
Q

What is the difficulty with post and pre translational processing

A

To predict the functionality of proteins from only studying the genome. it can result to different structures and fucntions

19
Q

What are transposons

A

Segment of DNA that can move to another spot on the same or different chromosome

20
Q

Why do genomes get smaller overtime??

A

The lose of protein coding genes(pseudogenes)
accumulation of Mutations over time
Adaption to a new life style

21
Q

What are transposable and jumping genes

A

Found in chromosomes and plasmids and additional genes

22
Q

Why do genomes get larger?

A

Duplication, cute parts of genes and then insert somewhere else. Cut and paste and copy and paste. Transposons. Polypoildy and nondisjunctions

23
Q

Changes in genome size can influence evolution?

A

neofucntionaliation
Degreadtion
Subfuctionalization