Genetics and Evolution Flashcards
The combination of alleles one has at a given genetic locus.
Genotype
The observable manifestation of a genotype.
Phenotype
One dominant allele and one recessive allele.
Complete Dominance
More than one dominant allele.
Codominance
Has no dominant alleles; heterozygotes has intermediate phenotypes.
Incomplete Dominance
The proportion of a population with a given genotype who express the same phenotype.
Penetrance
The varying phenotypic manifestations of a given genotype.
Expressivity
States that an organism has two alleles for each gene, which segregate during meiosis, resulting in gametes carrying only one allele for a trait.
Mendel’s First Law (of segregation)
States that the inheritance of one allele does not influence the probability of inheriting a given allele for a different trait.
Mendel’s Second Law (of independent assortment)
This experiment demonstrated the transforming principle, converting non-virulent bacteria into virulent bacteria by exposure to heat-killed virulent bacteria.
Griffith Experiment
This experiment demonstrated that DNA is genetic material because degradation of DNA led to cessation of bacterial transformation.
Avery-MacLeod-McCarty Experiment
This experiment confirmed that DNA is genetic material because only radiolabeled DNA could be found in bacteriophage-infected bacteria.
Hershey-Chase Experiment
What are some nucleotide mutations?
- Point Mutations
- Frameshift Mutations
The substituting of one nucelotide for another.
Point Mutations
Moving the three-letter transcriptional reading frame.
Frameshift Mutations
A mutation that has no effect on the protein.
Silent Mutation
The substitution of one amino acid for another.
Missense Mutation
The substitution of a stop codon for an amino acid.
Nonsense Mutation
Result in a shift in the reading frame of genes, leading to changes for all downstream amino acids.
Insertions/Deletions
Mutations that include much larger-scales and affect whole segments of DNA.
Chromosomal Mutations
What are some chromosomal mutations?
- Deletion mutations
- Duplication mutations
- Inversion mutations
- Insertion mutations
- Translocation mutations
Occurs when a large segment of DNA is lost.
Deletion Mutations
Occurs when a segment of DNA is copied multiple times.
Duplication Mutations
Occurs when a segment of DNA is reversed.
Inversion Mutations