Genetics

Question 1

HLH 5 genes AR

Answer 1

The five genes most commonly associated with
hemophagocytic lymphohistiocytosis (HLH) are:

MUNC13-4, STXBP2, RAB27A, STX11, and PRF1.

Question 2

HLH EBV genetics

Answer 2

EBV-associated HLH
SH2D1a (XLP-1)
or the BIRC4 (XLP-2) gene defects

. In the case of XLP-1, the gene is X-linked.