GENETICS

Question 1

MC genetic cause of infertility and hypogonadism in men

Answer 1

Klinefelter Syndrome

47 XXY

Question 2

Males with Klinefelter syndrome have

A. Hypergonadotropic hypogonadism
B. Hypogonadotropic hypogonadism
C. Hypergonadotropic hypergonadism
D. Hypogonadotropic hypergonadism

Answer 2

A. Hypergonadotropic hypogonadism

Question 3

Chromosomal abnormality

Down syndrome
Edwards syndrome
Patau syndrome
Klinefelter
Turner

Answer 3

Down syndrome Trisomy 21
Edwards syndrome Tri 18
Patau syndrome Tri 13
Klinefelter 47 XXY
Turner 45X0

Question 4

MC inborn error of beta oxidation

A. Medium chain acyl Co-A dehydrogenase
B. Short chain acyl Co-A dehydrogenase
C. Long chain acyl Co-A dehydrogenase
D. Very long chain acyl Co-A dehydrogenase

Answer 4

A. Medium chain acyl Co-A dehydrogenase
(MCAD)