ENDO

Question 1

Most common endocrine-matabolic disorder in childhood and adolescents

Answer 1

Type 1 DM

Question 2

Actual damage to the beta cells is B or T cells mediated?

Answer 2

T cell mediated

Question 3

How many % of B cell mass is damaged by the time clinical disease develops?
A. 50%
B. 60%
C. 70%
D. 80%
E. 90%

Answer 3

90%

Question 4

Indications for GH treatment. (7)

Answer 4

PINT GCS
1. Prader-Willi
2. Idiopathic short stature
3. Noonan syndrome
4. Turner syndrome
5. GH deficiency
6. Chronic renal failure
7. SGA with failure of catch-up growth

Question 5

Most common preventable cause of mental retardation

Answer 5

Congenital hypothyroidism

Question 6

The most serious complication of DKA and its treatment is:
A. Cerebral edema
B. cerebral herniation
C. Both
D. Neither

Answer 6

Cerebral edema and cerebral herniation.

Question 7

Characteristic of Wolfram Syndrome (4)

Answer 7

DIDMOD: diabetes insipidus, diabetes mellitus,
optic atrophy, deafness
> Autosomal recessive

Question 8

The clearest evidence of a role for viral infection in human T1DM is seen in which virus?
A. Cytomegalovirus
B. Parvovirus
C. Rubella
D. Rubeola

Answer 8

Congenital Rubella Syndrome

Question 9

Autonomic system (neurogenic) symptoms are perceived at a plasma glucose concentration of _.

Answer 9

less than 55 mg/dL

Question 10

Cognitive function is impaired (neuroglycopenia) at a plasma glucose concentration of _.

Answer 10

less than 50 mg/dL

Question 11

MC cause of hypopituitarism

Answer 11

Craniopharyngioma