genetics Flashcards

1
Q

single nucleotide polymorphism (SNP)

A

diff in DNA sequence at the same site of genome btwn 2 diff people

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2
Q

double muscle cattle

A

myostatin stops muscle hypertrophy after birth

  • single point mutation GCGA ➔ GTGA disrupts myostatin
  • no control on muscle hypertrophy ➔ double muscled cattle
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3
Q

selective breeding traits

A
  • growth rate
  • food efficiency
  • muscle
  • marbling ability
  • coat color
  • disease resistance
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4
Q

genetic probability

A

actual and expected ratios of genotypes may not match in small populations, but in very large populations, actual ratio may come close to the expected

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5
Q

pedigree

A

genetic representation of a family tree that shows inheritance of a trait or disease across several generations

  • shows relationships between herd members & indicates which individuals have or carry the trait/disease
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6
Q

allele frequencys

A

proportion of a particular allele present in a population, for a specific locus

  • # of copies of an allele divided by the # of copies of all possible alleles at that particular locus in a population
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7
Q

genotype frequency

A

proportion of a particular genotype in a population, at a specified number of loci

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8
Q

Hardy-Weinberg equation

A

gives expected genotype frequency

  • p2 + 2pq + q2 = 1
  • genotypic value is the sum of the effects of each allele for that genotype
  • additive gene action: each allele present in an animal contributes to the phenotype in an additive manner
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9
Q

partial dominance

A

expression of the heterozygote is intermediate to the expressions of homozygous genotypes and more closely resembles the expression of the homozygous dominant genotype.

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10
Q

no dominance (incomplete dominance)

A

intermediate phenotype (blend)

  • exactly midway
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11
Q

overdominance

A

phenotype is more pronounced in a heterozygote than homozygote, but most closely resembles the expression of the homozygous dominant phenotype

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12
Q

epistasis

A

multiple genes interact to determine phenotype

  • ex: albino color in mice, where two recessive alleles at one locus affect expression all other coat color loci
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13
Q

law of segregation

A

two copies of a gene (1 maternal + 1 paternal) separate so that each gamete receives only one copy

  • mendel’s 1st law
  • Each gamete will have one allele at any given locus
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14
Q

law of independent assortment

A

alleles of different genes assort independently of one another during gamete formation

  • genetic recombination (crossing-over)
  • mendel’s 2nd law
  • allele pairs segregate independently of one another
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15
Q

quantitative traits

A
  • phenotypes show a continuous, numerical expression
  • bell curve
  • affected by combination of diff genes
  • phenotypes cannot be divided into a number of discrete classes only continuous range of measurements
  • determined by a large number of genes, each with a small effect
  • influenced by environmental factors
  • ex: height, weight, intelligence
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16
Q

additive gene action

A

each allele present in an animal contributes to the phenotype in an additive manner