Genetic Recombination And Mapping Flashcards
What did Morgan know about genetic recombination and mapping?
That during meiosis, crossing over between two homologous chromosomes could occur resulting in an exchange of genes between two homologous chromosomes
What was Morgan’s assumption?
That genes are arranged in a linear manner in chromosomes
When are genes more likely to be recombined?
The farther apart two genes are on a chromosome
What did A.H. Sturtevant predict about genetic recombination?
That a mathematical relationship exists between the distance separating two genes on a chromosome and the frequency of recombination between the genes
What did Sturtevants studies establish?
The rationale of genetic mapping techniques used today
What is an example of genetic mapping?
If two loci recombine with a frequency of 1% they are separated by a map distance of 1 centimorgan in distance
What unit is map distance measured in?
Centimorgans
What did Barbara McClintock do in 1931?
Provided a direct demonstration of recombination in con chromosomes
