Avery-Macleod-McCarty Experiment

Question 0

Avery-Macleod-McCarty did a _______ experiment similar to the experiment performed by _______ in _______

Answer 0

Transformation

Griffith

1928

Question 1

When did Avery-Macleod-McCarty do their experiment?

Answer 1

1944

Question 2

What did the Avery-Macleod-McCarty experiment demonstrate?

Answer 2

That DNA was the genetic material of inheritance

Question 3

What was the first step if the Avery-Macleod-McCarty experiment?

Answer 3

Removed protein from test extract and the extract still retained the transforming ability

Question 4

What was originally in the test extract?

Answer 4

No live cells, only DNA, RNA, and proteins

Question 5

What was the second step of their experiment?

Answer 5

Digested test extract with various enzymes

Question 6

What were the enzymes used, what type of enzyme, and what were the results with each enzyme?

Answer 6

Trypsin = protease : no effect on transforming ability

Chymotrypsin = protease : no effect on transforming ability

RNase = nuclease : no effect on transforming ability

DNase = nuclease : no longer retained transforming ability on the R-strain cells

Question 7

Based on the results with the _______ enzyme, _______ was identified as the genetic material

Answer 7

DNase

DNA