General pharmacology Flashcards

0
Q

Cytochrome P450 inhibitors

A

“Inhibitors Stop Cyber Kids from Eating GRApefruit”

Isoniazid
Sulfonamides
Cimetidine
Ketoconazole
Erythromycin
Grapefruit juice
Ritonavir
Amiodarone
Quinidine
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1
Q

Cytochrome P450 inducers

A

“Ethel Booba takes PhenPhen and Refuses Greasy Carb Shakes”

Ethanol
Barbiturates
Phenytoin
Rifampicin
Griseofulvin
Carbamazepine
St. John's Wort/Smoking
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2
Q

Route of drug administration with partial avoidance ofnfirst pass effect

A

Rectal

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3
Q

Route of drug administration with 100% bioavailability

A

IV

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4
Q

Phase of drug study with ‘small number of normal volunteers’

A

Phase I

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5
Q

Phase of drug study with ‘post marketing surveillance’

A

Phase IV

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6
Q

Phase of drug study with “does it work properly”

A

Phase II

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7
Q

Phase of drug study with ‘randomized, double blind, control trials’

A

Phase III

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8
Q

Drug for a rare disease

A

Orphan annie drug

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