General info Flashcards
Parasympathetic receptors
neuroreceptor: ACh
receptors: Nicotinic, Muscarinic
Nicotinic receptors
Nm = muscle Nn = nerves
Muscarinic Receptors
M1-M5
M1 = CNS and GI
M2 = heart; CNS; stomach; intestine; bladder
M3 = mainly glands and smooth muscle; also GI and bladder smooth muscle contraction
Sympathetic Receptors
Neuroreceptor ACh»_space; NE
Receptors: alpha and Beta
Alpha receptors
a1: mainly vascular smooth muscle
a2: presynaptic junctions to influence NE release
Beta receptors
B1: heart, kidney
B2: skeletal muscle blood vessels, bronchial smooth muscles
B3: adipose tissue
Parasympathetic generic name
Cholinergic
Sympathetic generic name
Adrenergic (Catecholamines_
Cholinergic muscarinic response to stim
visceral and bronchiole smooth muscle: contraction
Cardiac muscle: dec HR
Exocrine glands: Increased secretions
Sweat glands: increased secretion
Alpha 1 response to stim
vascular smooth muscle - contraction
Alpha 2 response to stim
CNS inhibit neurons - decrease symp discharge from the CNS
B1 response to stim
Cardiac muscle increase HR and contract
Kidney increased renin
B2 response to stim
Bronchiole smooth muscle bronchodilation
Uterine relaxation
Anticholinergic AE
ABCDs Agitation Blurred vision Constipation Dry mouth Stasis of urine and sweat
Cholinergic AE
DUMBELLSs Diarrhea Urination Miosis Bradycardia Emesis Lacrimation Lethargy Salivation Sweating