General Anaesthesia

Question 1

3 commonly used IV induction agents?

Answer 1

Propofol
Thiopentone
Etomidate

Question 2

Name 4 inhalational agents?

Answer 2

Nitrous oxide
Isoflurane
Sevoflurane
Desflurane

Used to induce anaesthesia in children
More commonly used to maintain anaesthesia

Question 3

Define GA

Answer 3

Reversible, drug induced loss of consciousness, usually to allow a surgical procedure to be performed.

Question 4

Use of entonox?

Answer 4

50:50 nitrous: oxygen

For analgesia, labour and trauma

Question 5

MoA of anaesthetics?

Answer 5

Allosterically activate the GABAa receptor

This allows Cl- to enter the cell –> INHIBITION NEURONAL EXCITABILITY

Question 6

Action of ketamine and NO

Answer 6

Inhibit the NMDA (glut, +ve) receptors which would normally excite neuro-transmission

Question 7

Learning point:
Virtually all anaesthetic agents will to a greater or lesser effect have a negative inotropic effect on the heart and will reduce systemic vascular resistance.
Exception: ??

Answer 7

Ketamine