GENERAL Flashcards

1
Q

Which hormone can be used to to assess ovarian reserve prior to in vitro fertilisation treatment?

A

anti-mullerian hormone

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2
Q

Contra-indication to HRT

A
Active or recent arterial thromboembolic disease (e.g. angina or MI) 
Current or past breast cancer
Any oestrogen-sensitive cancer
Undiagnosed vaginal bleeding
Untreated endometrial hyperplasia
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3
Q

How long is the female urethra?

A

3-4 cm

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4
Q

When does the bladder produce desire to void?

A

250ml

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5
Q

What is polyuria?

A

when over 2.8l is produced in 24 hours

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6
Q

What will reduce efficacy of COCP?

A

phenytoin

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7
Q

Which drugs are contra-indicated in breast-feeding?

A
tetracyclines, ciprofloxacin, chloramphenicol, sulphonamides
pheobarbitone
amiodarone
cytotoxics eg methotrexate
lithium, benzodiazepines
bromocriptine
aspirin
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8
Q

A 40 year old woman who smokes 20 cigarettes a day complains of a green nipple discharge and a non-tender lump below the nipple.

A

duct ectasia

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9
Q

70 yr old woman presents with hot tender breast with cellulitis

A

inflammatory breast cancer

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10
Q

What proportion of couples suffer from infertility?

A

1 in 6

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11
Q

LH surge occurs at what duration prior to Ovulation ?

A

24- 36 hours

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12
Q

Treat infertility due to PCOS

A

Clomifene citrate

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13
Q

Where does spermatogenesis occur in a testicle ?

A

seminiferous tubules

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14
Q

What does
a) oligoasthenospermia
b) teratoasthenospermia
mean?

A

a) low count and motility

b) abnormal form and low motility

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15
Q

Where is testosterone secreted from in a male ?

A

leydig cell

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16
Q

A woman presents with at 7 weeks gestation with heavy vaginal bleeding and abdominal pain. On examination, her cervix is slightly open with tissue visible. On ultrasound scan a fetal heart beat is seen in the uterine cavity

A

inevitable miscarriage as cervix open

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17
Q

The rectouterine pouch (of Douglas) can be drained via a needle passed through….

A

the posterior fornix of the vagina

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18
Q

most effective form of contraception?

A

implant

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19
Q

the COCP is protective against which form of cancer?

20
Q

form of miscarriage where sac is still there

A

missed miscarriage

21
Q

is mesonephric or pasamesonephric duct present in females?

A

paramesonephric

22
Q

What does the mesonephric duct form?

A

vas deferens

23
Q

fluid in the foetal lung is mostly made by

A

the foetal lung

24
Q

resuscitation of term infants should use what

25
resuscitation of preterm infants should use what
low conc oxygen (20-30%)
26
A previously well newborn term infant on the postnatal ward is noticed to be breathing quickly and feeding poorly. Which condition[s] might be considered in your differential diagnosis?
group B strep
27
What drugs are contraindicated in pregnancy?
ACE inhibitors/ARB Renal hypoplasia Androgens Virilisation of female foetus Antiepileptics Cardiac, facial, limb, neural tube defects Cytotoxics Multiple defects, abortion Lithium Cardiovascular defects Methotrexate Skeletal defects Retinoids Ear, cardiovascular, skeletal defects Warfarin Limb and facial defects
28
treat primary amenorrhoea caused by prolactinoma
dopamine agonist eg cabergoline
29
Which contraception should be stopped at age 50?
COCP | injectable depo-provera
30
Benign cancer that affects all germ cell layers in the ovaries
dermoid cyst
31
abnormal endometrial thickness
pre-menopause: >16mm | post-menopause: >4mm
32
follow-up management of ectopic pregnancy
if methotrexate do LFTs
33
Which type of HRT is used in post-menopausal women who have had a hysterectomy?
oestrogen only
34
Which type of cancer is increased by combined HRT?
breast
35
Manage 1 missed pill in week 1
take extra pill
36
Manage 2 missed pill in week 1
emergency contraception
37
Manage 2 missed pill in week 2
use condoms for 7 days
38
Manage 2 missed pill in week 3
ok, no break after pack
39
Absolute CI to COCP
Hx of stroke or VTE migraines >35 and smoking >15 cigarettes
40
When can POP be started after giving birth?
anytime
41
When can depo be started after giving birth?
anytime unless breastfeeding
42
How long should COCP be avoided after giving birth?
3wks | 6wks if additional VTE risk
43
How long after UPSI should levonorogestrel be given?
upto 72hrs but efficacy dec with inc time
44
How long after UPSI should ulipristal be given?
upto 120 hrs (5 days)
45
In which form of emergency oral contraception is dose doubled if high bmi or enzyme inducing drugs?
levonorogestrel
46
In which form of emergency oral contraception is only one dose allowed per cycle?
ulipristal