Gene Linkage Flashcards

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1
Q

The diagnosis of Down syndrome is made by examining the individuals …

A

karyotype

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2
Q

Chromosome abnormalities result from nondisjunction, illustrating the importance of the orderly ….. and …. of genetic material during …. .

A

seperation, distribution

Meiosis 1

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3
Q

Genetic recombination occurs during the

A

prophase of meiosis 1

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4
Q

Many chromosomes are not involved in the human population because of legal …. of the … during early ….

A

Abortion embryo development

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5
Q

trisomy and monosomy can result from accidents that occur during meiosis during

A

nondisjunction of chromosomes

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6
Q

Half babies are male and female because of the … of the X and Y chromosome during …. meiosis

A

segregation, male

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7
Q

each person has at most … …. per trait

A

2 alleles

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8
Q

The time to observe sizes and shapes of chromosomes is during ..

A

metaphase

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9
Q

The resulting aniplody of a person with Klinefelters disease is caused by

A

nondisjunction

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10
Q

Half of all human cancers have … associated with their cells

A

p53

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11
Q

Sex in humans is determined by a gene on the …

A

Y chromosome

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12
Q

A linkage group goes with a … of genes on the same chromosome

A

group

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13
Q

Down syndrome is caused by an extra

A

21st chromosome

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14
Q

Recombination is most likely something that are ….

A

far apart

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15
Q

Nondisjunction is caused by

A

chromosomes that do not separate

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16
Q

Processes of Karyotyping

A
  1. Examine chromosomes in metaphase
  2. Add Giesma or fluoresant dye in order to stain the band on a chromosome, and identify the banding pattern
  3. They are set up in a karyogram, in which the chromosomes are set up based on size and position of centromere
  4. observed for chromosomal abnormally