Gene Expression

Question 1

one mRNA codes for many proteins

Answer 1

operon

Question 2

DNA can be released from binding to a histone by what type of reaction?

Answer 2

Acetylaction

Question 3

What is the most methylated base in DNA?

Answer 3

Cytosine –> forms 5-methylcytosine

Question 4

Prader-Willi syndrome and Angelman syndrome are due to

Answer 4

deletions associated with methylation

Question 5

VDJ recombination is associated with what?

Answer 5

Antibody production

Question 6

Fragile X syndrome is due to what type of mutation?

Answer 6

Triple repeat expansion

Question 7

Huntington disease is due to what type of mutation?

Answer 7

Triple repeat expansion

Question 8

Androgen Insensitivity is due to a lack of

Answer 8

Intracellular transcription factor receptors

Question 9

the ApoB100 gene causes a shortening of what?

Answer 9

mRNA after transcription

Question 10

Globin mRNa translation is regulated by what?

Answer 10

Heme inactivation of eIF2

Question 11

Increased iron levels does what to ferritin levels?

Answer 11

Increases

Question 12

miRNA’s do what?

Answer 12

induce degradation and repress translation

Question 13

includes a 5’ promoter (with operator region) sequence, followed by multiple structural genes

Answer 13

operon

Question 14

The formation of a hairpin structure, which effects the rate of translation, in RNA is an example of what during translation?

Answer 14

Attenuation

Question 15

cAMP-CRP binds at lac operator, recruiting RNA polymerase is an example of what kind of gene regulation?

Answer 15

Positive control

Question 16

Lac I gene product binds to operator region of Lac operon preventing transcription is an example of what kind of gene regulation?

Answer 16

Negative control

Question 17

Modification to histones (acetylation) alters the binding affinity for DNA to the histone shows what kind of Euk gene regulation?

Answer 17

Chromatin remodeling