Gastrulation Flashcards

1
Q

Which cell layer of the Bilaminar disc is ventral and which is dorsal?

A

Epiblast is dorsal
Hypoblast is ventral

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2
Q

When do syncytiotrophoblast and cytoptrophoblasts begin to undergo placentation?

A

In week 3

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3
Q

When does formation of the primitive streak begin?

A

Week 3

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4
Q

What is the primitive streak?

A

A slender midline structure with cellular enlargements surrounding it

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5
Q

What is the expansion of the primitive streak at the cranial end and what is the indentation called?

A

The primitive node and the primitive pit

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6
Q

When does development of the trilaminar disc begin?

A

Week 3

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7
Q

When does the future position of the cloacal membrane appear?

A

Week 3

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8
Q

What happens to cells in gastrulation?

A

Cells start to delaminate along the edge of the Bilaminar disc and move ventrally into the hypoblast layer. The new cell layer is the endoderm

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9
Q

What kind of cells fill the gap cause by gastrulation?

A

Mesodermal

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10
Q

What is ingression?

A

Movement and delimitation of cells between the endoderm and ectoderm

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11
Q

Where does the prechordal plate develop?

A

Along the primitive streak

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12
Q

What cranial structure do cells move towards from the primitive streak during ingression?

A

The oropharyngeal membrane

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13
Q

What is the function of the pre-chordal plate?

A

To act as an inducer to push the notochord up to the oropharyngeal membrane

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14
Q

What is the function of the neurenteric canal?

A

It allows communication between the amniotic cavity and yolk sac

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15
Q

What do the delaminated cells form during notochord formation?

A

A hollowed out tube

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16
Q

What happens to the tube formed by delaminate cells?

A

It starts to integrate with endoderm and flattens

17
Q

What do source signalling molecules cause?

A

Vertebral column and neural tube formation

18
Q

What is the function of the notochord?

A

To provide stability for developmental muscle attachment and to allow folding to occur around it

19
Q

At what day is the notochordal process clear?

A

Day 17

20
Q

What is the fate of the ectoderm?

A

Becomes epidermis, hair, nails, glands
Also nervous system

21
Q

What are the 3 regions of the intraembryonic mesoderm?

A

Paraxial, intermediate and lateral plate mesoderm

22
Q

What is the fate of paraxial mesoderm?

A

Axial skeleton (not cranium)
Majority skeletal muscle
Some of teh dermis of the central back
Somites

23
Q

What are somites?

A

Balls of cells with mesenchymal interiors

24
Q

What is the fate of intermediate mesoderm?

A

Urogenital system - kidneys, ureter, reproductive system

25
Q

What is the fate of lateral plate mesoderm?

A

Somatic areas form majority of the dermis, lining body wall, bones upper and lower limbs
Visceral areas form cardiovascular system, mesothelial covering organs, smooth muscle

26
Q

What is the fate of endoderm?

A

Lining gut tube, respiratory tract, bladder and urethra