Cardiovascular Development Flashcards
When does the primary heart field develop?
Week 3
What does the truncus arteriosus become?
Aorta and pulmonary trunk
What does the bulbus cordis become?
Right ventricle and outflow tract
What does the primitive ventricle become?
The left ventricle
What does the primitive atrium become?
The right and left atria
What does the sinus venosus become?
Coronary sinus, oblique vein, smooth part right atrium
After heart folding what is the proximal part of the outflow tract?
Conus arteriosus
What is the distal part of the outflow tract after heart folding?
Truncus arteriosus
What is the function of foramen ovale?
Allow blood flow from right to left side of the heart
What does the sinus venosus become?
The sinus venarum in the right atrial wall
What do the vessels that come in and out of the sinus venosum become?
SVC and IVC
How do the Pulmonary veins develop?
As a single vein at week 5 that will divide twice to give 4 veins that feed into a single pulmonary vein. Openings become integrated into left atrium
Where and when does the formation of the first blood cells occur?
In mesoderm of yolk sac in week 3
What cells are made form the yolk sac mesoderm?
Hemangioblasts
What do hemangioblasts become?
Haematopoeitic stem cells and endothelial precursor cells
How are blood vessels formed?
Mesoderm of yolk sac become blood cells. Hemangioblasts from same mesoderm and become stem cells. Stem cells surround blood cells and form blood vessel