Gastrointestinal Week 3 Flashcards
What’s is charcots triad and its significance?
Jaundice, fever, rigors. Suggests cholangitis
what kind of organ typically cause colicky pain
hollow, tube muscular type organs like bowel, or gall bladder
how what a peritonitis pain present
patient would say that pain is worse on movement
what kind of pain will start at the front at go to the back and to the right shoulder?
gallbladder
where does pancreas pain often radiate to
to the back
an abdominal pain that comes and stays at around the same intensity in the epigastric region - what is the first ddx?
peptic ulcer
what kind of pain is acute cholescytistis
constant pain
what foods often aggravate cholescystitis
fatty foods
what kind of foods will aggravate a peptic ulcer
citrus, spicy food
where in the GI would melena suggest its origin from?
upper GI
what pathology is tenesmus associated with
cancer
colitis
IBS
what is GET SMASHED
risk factors for pancreatitis
gall stones
ethanol
trauma
steroids mumps autoimmune scorpion venom hyperlipidaemia/hypercalcaemia/hyperparathyroidism ERCP Drugs
why do you get swollen ankles with hepatitis
reduced albumin synthesis
what GI diseases are related to clubbing
IBD (crohns, UC), primary biliary cirrhosis, malabsorption (celiac), cirrhosis
difference between telangiectasia and spider naevi
telangiectasia fill from outside in. spider naevi from inside out. can differentiate by pressing on it
what are kayser fleischer rings indicative of
wilsons disease, copper retention
what does angle stomatitis indicate
iron deficiency anaemia
what does glossitis indicate
iron/b12/folate deficiency
what is rovsing’s sign
push left side, if right side pain then positive rovsing sign, may be appendicitis
complications with GORD
esfgitis
peptic ulcer
benign strictures
barrett’s esfgs
difference between duodenal ulcer and peptic ulcer in regards to pain relief
duodenal ulcers are usually relieved by eating, vs peptic ulcers which are often relieved by lying down or vomiting
complications in peptic ulcer
erosion, perforation, peritonitis
difference between crohn’s and UC
UC assoc w cancer
crohns have skip lesions, UC is continuous
Uc affects large colon, crohn’s anywhere in GI
crohn’s affect transmurally, while UC is just surface
bloody stool is common in UC or CD?
UC
how does CF affect the pancreas
thickened secretions block ducts
what are the SSS CCC TTT F to describe a lump
size
shape
site
color
consistency
contour
transilluminance
tethering
tenderness
fluctuance
contents of the spermatic cord
piles dont contribute to a good sex life
pimpiniform plexus ductus deference cremasteric artery testicular artery artery of ductus deferens genital branch of the genito femoral nerve sympathetic nerves lymphatics
what forms the inguinal canal? (ant/post/floor/roof)
anterior wall - external oblique
posterior - fascoa transversalis
roof - conjoint tendon
floor - inguinal ligament
difference between a direct and indirect hernia
direct hernia goes through the abdominal wall away from the inguinal canal
indirect hernia goes through the deep ring of the inguinal canal and out through the superficial ring
where does a femoral hernia happen
below inguinal canal, lateral to pubic tubercle, through femoral ring and into femoral canal
how to conduct a hernia exam
patient standing, expose testicles if male
inspect patient, cough
palpate lump
lie down, fingers on lump and cough, if hernia reappears is direct hernia
3 things that can happen to a hernia
reducible - can be pushed back in
incarcerated - stuck between structures
strangulated - stuck with blood flow cut off
what does a bag of worms in the testicles mean
varicocele (enlargement of pampiniform plexus)
who gets femoral hernias more often
women
what position should a patient be in when doing a DRE
lying on side with knees tucked in
what is hematochezia
fresh red blood from rectum with stool
what is the most common cause of UGI bleeding
Peptic ulcer disease
what kind of bleed arises from a PUD bleed
fresh red blood
what is a mallory weiss tear
tear in esfgs at junction between stomach and esfgs
what bloods are important in massive GI bleed cases
HB, ABG, cross match, LFTs, coagulation
what is “fluid challenge”?
give 500ml crystalloid then assess condition again after
noteworthy history to take in GI bleed case
previous episode previous endoscopy drug history chronic liver dz state family history
what drugs can exacerbate GI bleeds
antiplatelets
anticoagulatives
options for treating GI bleed after initial stabilisation
endoscopic therapy including adrenaline injection in situ, heat energy therapy, clips
what drugs should be prescribed after PUD bleed?
IV PPI for 3 days
antibiotics if H pylori +ve
how large dilatations in small and big bowel to be considered obstruction
> 6cm for colon, >9cm for caecum
>3cm in small bowel in at least 3 places
what level is the transpyloric plane (rib and spinal level)
L1 // 9th rib
which vein supply the portal vein
sup and inferior mesenteric veins
why do you get dark urine and pale stools in biliary obstruction?
bilirubin is usually excreted through the faeces through a process done by the liver, however in biliary obstruction, the bilirubin is unable to reach the intestine and hence high amounts of soluble conjugated bilirubin enter the circulation which are then excreted by the kidneys.
pale stools because the bilirubin is unable to reach the stools
genetic mutation that causes decreased activity of protein which helps conjugate bilirubin in the liver, leading to impaired excretion and build up
what is gilbert’s syndrome
route of transmissions of hepatitis viruses A B C E
A and E, oral faecal, shellfish and pork
B blood born/sex IVDU
C IVDU, blood, sex
how does sphincter of oddi dysfunction cause issues
failure to relax causes build up of bile in the CBD
what is courvoisier’s law
painless jaundice + palpable GB = malignancy of pancreas or biliary tree, until proven otherwise
which cells in the pancreas are responsible for its exocrine and endocrine functions
islets of langerhans - endocrine
acinar cells - exocrine
loss of pancreatic function leads to what kind of stool?
steatorrhea
what imaging can be used for pancreatic investigations
CT/MRCP
EUS
what levels are tested for in LFTs (5)
GGT ALT Alk phos albumin bilirubin
what is the most reliable marker of liver function
PT/INR
what is the healthy range for INR in a normal person and someone on warfarin
<1.1 for normal
2-3.0 for warfarin therapy