Gastrointestinal perforation Flashcards
What is gastrointestinal (GI) perforation?
1 - opening in GI leaking GI contents
2 - obstruction of GI
3 - inflammation of peritoneum cover GI
4 - malignancy of GI
1 - opening in GI leaking GI contents
Which of the following is likely to cause ischaemia, which can subsequently lead to GI perforation?
1 - appendicitis, diverticulitis, colitis
2 - malignancy, inflammatory bowel disease
3 - obstruction or vascular (peripheral vascular disease)
4 - iatrogenic or trauma
3 - obstruction or vascular (peripheral vascular disease)
Which of the following is likely to cause infection, which can subsequently lead to GI perforation?
1 - appendicitis, diverticulitis, colitis
2 - malignancy, inflammatory bowel disease
3 - obstruction or vascular (peripheral vascular disease)
4 - iatrogenic or trauma
1 - appendicitis, diverticulitis, colitis
Which of the following is likely to cause erosion of the GI, which can subsequently lead to GI perforation?
1 - appendicitis, diverticulitis, colitis
2 - malignancy, inflammatory bowel disease
3 - obstruction or vascular (peripheral vascular disease)
4 - iatrogenic or trauma
2 - malignancy, inflammatory bowel disease
Which of the following is likely to cause physical disruption of the GI, which can subsequently lead to GI perforation?
1 - appendicitis, diverticulitis, colitis
2 - malignancy, inflammatory bowel disease
3 - obstruction or vascular (peripheral vascular disease)
4 - iatrogenic or trauma
4 - iatrogenic or trauma
Is oesophageal perforation common?
- no
Hows many patients present with oesophageal perforation each year?
1 - 3000
2 - 30,000
3 - 300,000
4 - 3,000,000
4 - 3,000,000
- little more common in men
What age does oesophageal perforation more commonly occur in?
1 - >30y/o
2 - >40y/o
3 - >50y/o
4 - >60y/o
4 - >60y/o
What is the mortality of oesophageal perforation?
1 - 0.2%
2 - 2%
3 - 20%
4 - 50%
3 - 20%
What is the most common cause of oesophageal perforation?
1 - iatrogenic
2 - malignancy
3 - spontaneous
4 - trauma
1 - iatrogenic
- generally during dilation or surgery accounting for around 50-60%
15% of oesophageal perforation is spontaneous. What is the most common cause?
1 - iatrogenic
2 - intense vomiting/retching
3 - malignancy
4 - trauma
2 - intense vomiting/retching
- sudden increase in intraesophageal pressure combined with relatively negative intrathoracic pressure caused by straining or vomiting.
- called Boerhaave syndrome
In addition to iatrogenic and spontaneous oesophageal perforation, which of the following is not a common cause?
1 - foreign bodies
2 - malignancy
3 - causative liquids (alkaline especially)
4 - infection
4 - infection
There are a number of symptoms that can present in a patient with oesophageal perforation. Which of the following is NOT a common presentation?
1 - chest pain
2 - back/shoulder pain
3 - peripheral oedema
4 - vomiting
5 - subcutaneous emphysema (air in tissue under the skin)
6 - SOB and generally unwell
3 - peripheral oedema
There are a number of symptoms that can present in a patient with oesophageal perforation. Macklers triad is often used to identify those who may have
perforated their oesophagus. Which of the following is NOT part of this triad?
1 - vomiting
2 - chest pain
3 - peripheral oedema
4 -subcutaneous emphysema (air in tissue under the skin)
3 - peripheral oedema
If we suspect a patient has a perforated oesophagus, what imaging modality is often the first choice?
1 - ultrasound
2 - chest X-ray
3 - CT scan
4 - MRI scan
2 - chest X-ray
- can often see pleural effusion, air in mediastinum or subcutaneous emphysema
If we suspect a patient has a perforated oesophagus, the first choice imaging is a chest X-ray. What is the gold standard to diagnosis patients?
1 - ultrasound with contrast
2 - chest X-ray or CT with contrast
3 - CT scan with contrast
4 - MRI scan with contrast
2 - chest X-ray or CT with contrast
- water soluble iodine
If we suspect a patient has a perforated oesophagus, the first choice imaging is a chest X-ray, and the gold standard to diagnosis patients is a chest X-ray or CT with contrast. Why can endoscopy often be useful?
1 - has diagnostic potential
2 - more accurate images
3 - no radiation
4 - has diagnostic and therapeutic potential
4 - has diagnostic and therapeutic potential
If a patient has small defects causing a perforated oesophagus, what is the medical clinical management?
NMB = nill by mouth
IV - intravenous
1 - NMB and IV antibiotics
2 - fluids only, IV antibiotics, drainage of collections
3 - NMB, IV antibiotics, drainage of collections
4 - NG tube, IV antibiotics, drainage of collections
3 - NMB, IV antibiotics, drainage of collections
- if the medical conservative approach fails then surgery will be required
- drainage of infection is key
- VERY HIGH MORTALITY
What is the most common cause of upper GI perforation?
1 - iatrogenic
2 - infection
3 - ischaemia
4 - peptic ulcer
4 - peptic ulcer
What is the incidence of gastric/duodenal perforation?
1 - 1-2 per 100,000/year
2 - 4-11 per 100,000/year
3 - 30-50 per 100,000/year
4 - 100-150 per 100,000/year
2 - 4-11 per 100,000/year
Why is the incidence of gastric/duodenal perforation reducing?
1 - reduced alcohol intake
2 - reduced BMIs
3 - reduced smoking
4 - increased use of PPIs
4 - increased use of PPIs
What is the mortality of gastric/duodenal perforation?
1 -1-5%
2 - 5-10%
3 - 15-20%
4 - 20-30%
3 - 15-20%
Peptic ulcer is the most common cause of upper GI perforation, what is the leading cause?
1 - NSAIDs
2 - smoking
3 - Helicobacter pylori
4 - alcohol
3 - Helicobacter pylori
- 90-95% of duodenal ulcers
- 70-85% of gastric ulcers
Peptic ulcer is the most common cause of upper GI perforation, with the leading cause being Helicobacter pylori. Which if the following is NOT anther risk factor for a peptic ulcer?
1 - NSAIDs
2 - smoking
3 - steroids
4 - alcohol
4 - alcohol