Gastrointestinal - Gall Bladder Flashcards
1
Q
what occurs in PBC?
A
interlobular bile ducts damaged due to chronic autoimmune granulomatous inflam
2
Q
risk factors for PBC?
A
AI disease old female hypercholesterolaemia FHx smoking
3
Q
features of PBC?
A
itch fatigue dry eyes/mouth xanthelasma hepatomegaly malabsorption
4
Q
what complications can occur in PBC?
A
fibrosis
cirrhosis
portal hypertenion
5
Q
Ix in PBC and results?
A
LFTs (all raised) Bilirubin (raised) albumin (low) PT (raised) AMA
6
Q
Tx for PBC?
A
urseodeoxycholic acid/colestyramine for itch
vitamins
monitor
7
Q
what occurs in PSC?
A
inflammation and fibrosis of intra/extra hepatic bile ducts
8
Q
risk factors for PSC?
A
UC
male
HLA
FHx
9
Q
features of PSC?
A
itch fatigue wt loss jaundice abdo pain
10
Q
Ix for PSC?
A
LFTs (all raised)
ERCP
pANCA (positive)
11
Q
what are those who suffer from PSC at risk of?
A
cholangitis
cholangiocarcinoma
