Gastrointestinal - Acute Liver Disease Flashcards

1
Q

features of autoimmune hepatitis?

A
hepatmegaly 
jaundice
stigmata of CLD
malaise
abdo pain 
amenorrhoea
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2
Q

who gets type 1 autoimmune hepatitis and who gets type 2?

A

1 - adults

2 - kids

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3
Q

what is autoimmune hepatitis associated with?

A

other AI conditions

female

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4
Q

what markers are seen in type 1 autoimmune hepatitis?

A

ANA

ASMA

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5
Q

what markers are seen in type 2 autoimmune hepatitis?

A

anti LKM1 antibodies

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6
Q

Ix for autoimmune hepatitis and results?

A

LFTs (raised AST and ALT)
IgG (raised)
biopsy

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7
Q

Tx for autoimmune hepatitis?

A

steroids
AZA
transplant

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8
Q

what is the spread for each type of hepatitis?

A
A - faecal oral
B - blood
C - blood
D - co infection with B
E - faecal oral
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9
Q

what Ix is done for hepatitis D?

A

anti HDV antibodies

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10
Q

what Ix is done for hepatitis C?

A

anti HCV antibodies

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11
Q

what Ix is done for hepatitis A?

A

LFTs (AST and ALT rise)

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12
Q

Tx for hepatitis A?

A

supportive

self limiting

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13
Q

what hepatitis have vaccines offered?

A

A

B

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14
Q

what is the Tx for hep B?

A

antivirals

monitor for hepatocellular carcinoma (AFP/US)

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15
Q

what hepatitis can cause chronic liver failure?

A

B/C

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16
Q

what blood test shows the person has been vaccinated/immune from hep B?

A

anti HBs

17
Q

causes of pre hepatic jaundice?

A

haemolytic

sickle cell
thalassaemia
post transfusion
G6PDD

18
Q

causes of hepatocellular jaundice?

A
viral hepatitis
autoimmune hepatitis
wilsons
haemochromatosis
cirrhosis
ALD
19
Q

causes of obstructive jaundice?

A

biliary colic

cholangiocarcinoma

20
Q

what test shows acute hepatitis B infection?

A

IgM anti HBc

21
Q

what test shows past hepatitis B infection?

A

IgG anti HBc

22
Q

who gets alcoholic hepatitis?

A

heavy drinkers

23
Q

features of alcoholic hepatitis?

A
nausea
anorexia
RUQ pain 
fever
ascites
sore hepatomegaly
24
Q

Tx for alcoholic hepatitis?

A

supportive
NG tube
steroids
pabrinex