Gastrointestinal - Acute Liver Disease Flashcards
features of autoimmune hepatitis?
hepatmegaly jaundice stigmata of CLD malaise abdo pain amenorrhoea
who gets type 1 autoimmune hepatitis and who gets type 2?
1 - adults
2 - kids
what is autoimmune hepatitis associated with?
other AI conditions
female
what markers are seen in type 1 autoimmune hepatitis?
ANA
ASMA
what markers are seen in type 2 autoimmune hepatitis?
anti LKM1 antibodies
Ix for autoimmune hepatitis and results?
LFTs (raised AST and ALT)
IgG (raised)
biopsy
Tx for autoimmune hepatitis?
steroids
AZA
transplant
what is the spread for each type of hepatitis?
A - faecal oral B - blood C - blood D - co infection with B E - faecal oral
what Ix is done for hepatitis D?
anti HDV antibodies
what Ix is done for hepatitis C?
anti HCV antibodies
what Ix is done for hepatitis A?
LFTs (AST and ALT rise)
Tx for hepatitis A?
supportive
self limiting
what hepatitis have vaccines offered?
A
B
what is the Tx for hep B?
antivirals
monitor for hepatocellular carcinoma (AFP/US)
what hepatitis can cause chronic liver failure?
B/C
what blood test shows the person has been vaccinated/immune from hep B?
anti HBs
causes of pre hepatic jaundice?
haemolytic
sickle cell
thalassaemia
post transfusion
G6PDD
causes of hepatocellular jaundice?
viral hepatitis autoimmune hepatitis wilsons haemochromatosis cirrhosis ALD
causes of obstructive jaundice?
biliary colic
cholangiocarcinoma
what test shows acute hepatitis B infection?
IgM anti HBc
what test shows past hepatitis B infection?
IgG anti HBc
who gets alcoholic hepatitis?
heavy drinkers
features of alcoholic hepatitis?
nausea anorexia RUQ pain fever ascites sore hepatomegaly
Tx for alcoholic hepatitis?
supportive
NG tube
steroids
pabrinex
