gastrointestinal drugs

Question 1

antacids

method of action:

uses:

side effects:

contraindications:

example:

Answer 1

Method of Action: Direct chemical action to neutralise excess stomach acid

Uses: GORD or peptic ulceration

Side effects: Bloating, Diarrhoea and Stomach Cramps

Contraindications: Kidney disease with reduced function, high blood sodium, visible water retention

Example: Milk of Magnesia

Question 2

proton pump inhibitors

Method of Action:

Uses:

Side effect:

Contraindications:

Example:

Answer 2

Method of Action: Block the gastric Na+/K+ pump of the parietal cells of the stomach

Uses: GORD or peptic/duodenal ulceration

Side effect: Bloating, Diarrhoea and Stomach Cramps

Contraindications: If there is a known hypersensitivity reaction to ay of the ingredients

Example: Omeprazole or lansoprazole (Ends in –Prazole)

Question 3

histamine 2 receptor antagonists

Method of Action:

Uses:

Side effect:

Contraindications:

Example:

Answer 3

Method of Action: Block the histamine receptor in the stomach so there is reduced acid production

Uses: GORD or peptic/duodenal ulceration

Side effect: Bloating, Diarrhoea or Stomach Cramps

Contraindications: Kidney disease with reduced function and stomach cancer

Example: Cimetidine