Gastroenterology 3.0 Flashcards

1
Q

Which treatment is recommended acutely for a patient with severe alcoholic hepatitis?

A

Prednisolone.

Corticosteroids improve outcomes!

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2
Q

What is the main supplier of blood to the intestines?

A

Superior mesenteric artery

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3
Q

Why is there collateral circulation of the mesenteric arteries?

A

Because the small bowel has a high O2 demand and therefore a high ischaemic risk! COllateral circulation attempts to diminish that risk

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4
Q

Small bowel ischaemia can go be ____- and _______depending on the layers. What are the dangers of the second option?

A
  • Mucosal
  • Transmural
    • ileus
    • break on bowel wall >> peritoneal space leakage > potential sepsis
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5
Q

What are the subtypes of causes for small bowel ischaemia?

A
  • Occlusive
    • thrombus
    • thromboembolus of SMA
    • cancer
    • hernia
    • vulvular
    • intersusseption
  • Non-occlusive
    • hypovolemia
    • low CO
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6
Q

Grey turners is a sign of? (flank bruising)

A

patients with severe haemorrhagic pancreatitis.

In this situation the major vessels surrounding the pancreas bleed. The pancreatitis process also results in local fat destruction, this results in blood tracking in the tissue planes of the retroperitoneum and appearing as flank bruising.

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7
Q

Murphy’s sign is what, and what is it a sign of?

A

it’s a sign of cholecysitis where pain/catch of breath elicited on palpation of the right hypochondrium during inspiration.

Because the infected gallbladder causes inflammation of the parietal peritoneum

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8
Q

Above and medial to pubic tubercle
Strangulation is rare

What hernia is this??

A

Inguinal hernia! (most common)

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9
Q

What is the difference with direct and indirect hernias?

A

Indirect: come through the inguinal ring, lateral to the epigastric vessels

Direct: comes directly through abdo wall, medial to epigastric vessels

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10
Q

describe the classical picture of Hepatitis A

A

1-2 week incubation period

Flu like prior

Nausea, arthralgia, jaundice

organomegaly

****seafood, travelling all risks (faecal-oral route)

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11
Q

What does vitamin C deficiency (scurvy) do and how does it present

A

Causes defective collagen synthesis and poor capillary integrity >> poor wound healing and bleeding

  • Bleeding gums/haematuria/epistaxis
  • gingivitis/ loose teeth
  • poor wound healing
  • general malaise
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12
Q

clindamycin is associated with a high risk of….

A

clostridium difficile infection

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13
Q

what is “Globus pharyngis”

A

sensation of “lump in throat” when there is none.

saliva may be harder to swallow. Potential hx of anxiety

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14
Q

How does Loperamide actually work

A

through inhibition of opiod receptors within the bowel >> reducedgastric mobility

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15
Q

How do we test for liver cirrhosis

A

via transient elastography

brand name ‘Fibroscan’

A wave is passed into the liver from a small transducer on the end of an ultrasound probe

measures the ‘stiffness’ of the liver which is a proxy for fibrosis

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16
Q

H.pylori eradication is

A

PPi + amoxicillin + clarithromycin

or

PPi + metronidazole + clarithromycin

17
Q

what is the most prominent symptom of chrohns disease in children?

A

Abdominal pain

18
Q

What investigations should you do specifically for Chrohns

A
  • Faecal calprotectin
  • anaemia
  • raised inflamm marker
  • Low B12 and vit D
19
Q

When do you start thinking ischaemic colitis.

Where are you most likely to get it

A

history of ischaemic heart disease and hypertension an ischaemic cause of the pain is likely. Add to this the pain gets worse after eating, when the bowel requires more blood flow for its increased energy demands for digestion and ischaemic colitis would be the diagnosis to investigate first.

Think the splenic flexure or recto-sigmoid junction, as it is the most distally supplied area

20
Q

Between cholangitis, choledocolithiasis, cholecysitis and cholelithiasis how do these rank in severity, brief summary of and what treatment is required

A
  1. Cholangitis: inflammation of whole biliary tree due to choledocolithiasis
    1. ERCP urgen (they will be in pain)
  2. Choledocolithiasis: CBD stone, causing obstructive jaundice and mild inflammation
    1. ​ERCP
  3. Cholecysitis: Cystic duct stone causing an inflammed gall bladder, constant RUQ pain
    1. cholecystectomy
  4. Cholelithiasis: gallbladder stone, colicky RUQ pain
    1. elective cholecystectomy
21
Q

Cholelithiasis? Signs, symptoms, dx and Tx

A

Gallbladder stone

Signs

  • colicky RQ pain (cholesterol or pigment stone) worse with fatty food
  • RUQ USS shows acoustic shadowing
  • Nil fevers or systemic signs

Tx: elective cholecystectomy

22
Q

Cholecystitis? Signs, dx, Tx

A

Inflammation of the gallbladder due to a stone in the cystic duct

Signs:

  • constant RUQ pain
  • Fever, leukocytosis
    • murphy’s
  • RUQ USS or HIDA

Tx: Cholecystectomy

23
Q

Choledocolithiasis? Signs, dx, tx

A

Stone in the common bile duct

Signs:

  • Obstructive jaundice, pain, inflammation
  • Dilated biliary ducts on RUQ USS

Tx: ERCP

24
Q

Cholangitis? Signs, dx, tx

A

due to choledocolithiasis that has progressed to infection (ascended)

Signs:

  • Charcots Triad: fever, jaundice, RUQ
  • Reynolds Pentod: + hypotension, altered mental status

Tx: RUQ USS and urgent ERCP