Gastro-Intestinal Flashcards

1
Q

Acute Appendicitis

A

Patient who is a young adult complains of acute onset of periumbilical pain
-steadily getting worse over 12 to 24 hours
-pain starts to localize at McBurney’s point.

Classic exam findings:
-low-grade fever
-right lower quadrant (RLQ) pain (McBurney’s point)
-rebound and guarding.
-psoas and obturator signs are positive.

When the appendix ruptures, clinical signs of acute abdomen occur, such as involuntary guarding, rebound, and a boardlike abdomen. Refer to ED.

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2
Q

Rovsing sign

A

Rovsing/Reverse/Right

Palpate L lower quadrant and it hurts on Reverse/Right side

+ = Appendicitis

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3
Q

Markle sign

A

“Heel Jar”

Pain in R lower quadrant when pt hops on one foot

+ = Appendicitis

“megan dug her heel into Harry’s foot. he hopped up and down in pain”

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4
Q

Blumburg Sign

A

Rebound Tenderness

+ = Appendicitis

[ think”BLUMB!” is. the sound when doing the rebound ]

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5
Q

Mcburney’s Point

A

2/3 distance from navel to R axis.

Tenderness = Maximal

+ = Appendicitis

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6
Q

Psoas Sign

Oberator Sign

A

Psoas Sign
-raising leg against resistance = abdominal pain
“SO AS i was saying–> while keeping kids leg down”

Oberator Sign
-rotation of R hip 90’. Pain in lower quad

“sounds like “rotator”

+ = Appendicitis

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7
Q

Murphy’s Sign

if + then what?

why do imaging in this order?

A

“bear down to let out a MURPH…. offended them so bad he had to come to the US to HIDA”

Take deep breath and hold-
+ pain w/palpation R subcostal area

+ = Cholecystitis

if + then what?
-#1: we order an US (to see if its Gallstones)
then
-#2: HIDA scan

why do imaging in this order?
HIDA scan wont work if there are Gall Stones

-do US to check for gallstones first.

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8
Q

GERD

PPI or H2 Blocker?

PPI complications:

when to Refer?

what blood pressure med to avoid?

A

PPI or H2 Blocker?

H2 good for:
(“-tidines”)
—>mild symptoms
-no insurance
-B12 anemia
-osteoporosis
leo in the titanic; “He 2, would like Ti’DINE with us” who? this 12 year old? i feel it in my bones that he is not worthy”

PPI good for:
( “-prazole”)
—->more severe symptoms
-H2 doesn’t work
-these are more effective & more expensive
-take right before first meal of the day
-prescribed 4-8 wks
“PPI “prepare to be PRAZOLED”

PPI complications:
COB

-C-Diff
-Osteoporosis
-B12 Deficiency

when to Refer?
-when symptoms don’t resolve

what blood pressure med to avoid?
-CCB

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9
Q

Acute Cholecystitis

where is the pain?

A

-Overweight female patient complains of severe right upper quadrant (RUQ) or epigastric pain

-occurs within 1 hour (or more) after eating a fatty meal.
-Pain may radiate to the right shoulder.

-Accompanied by nausea/vomiting and anorexia. If left untreated, may develop gangrene of the gallbladder (20%). May require hospitalization

“when doing the murphy- i felt it in like my shoulder! stop holding your breath so much, your going to get gangrene”

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10
Q

Acute Diverticulitis

where is the pain?

signs of acute attack?

CBC will show?

tx?

A

Elderly patient with acute onset of high fever, anorexia, nausea/vomiting, and left lower quadrant (LLQ) abdominal pain.

Risk factors for acute diverticulitis include increased age, constipation, low dietary fiber intake, obesity, lack of exercise, and frequent nonsteroidal anti-inflammatory drug (NSAID) use.

Signs of acute abdomen are rebound, positive Rovsing’s sign, and a boardlike abdomen.

-Complete blood count (CBC) will show leukocytosis with neutrophilia and shift to the left.

-The presence of band forms signals severe bacterial infection (bands are immature neutrophils).

-Complications include abscess, sepsis, ileus, small-bowel obstruction, hemorrhage, perforation, fistula, and phlegmon stricture. May be life-threatening.

TX:
augmentin or Ciprofloxacin

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11
Q

Acute Pancreatitis

where is the pain?

Symptoms include:

Signs?

Labs used to assess the pancreas:

Causes:

Tx: What two things must you do?

A

Symptoms include:
-acute onset of fever, nausea, and vomiting
-pain in L UPPER QUADRANT
-rapid onset of abdominal pain that RADIATES TO the MIDBACK (“boring”) located in the epigastric region.
-guarding/tenderness
-positive CULLEN’s sign (blue discoloration around umbilicus)
-positive GREY TURNER’s sign (blue discoloration on the flanks).
The patient may have an ileus and show signs and symptoms of shock. Refer to ED

Labs used to assess the pancreas:
-Amylase
-Lipase

Causes:
-drugs (approximately 90% of cases of acute pancreatitis)
-Gall stone blockage
-increased Ca levels
-increased Triglycerides
-alcohol abuse.

Tx: What two things must you do?
Figure out cause
-stop drinking/ get Ca down/ etc
Manage symptoms:
-NPO (pancreas will stop producing digestive enzymes)
-pain control
-stay hydrated
-antibiotics
-decrease fat in diet

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12
Q

Clostridium Difficile Colitis

s/s

causes

Tx

A

-Severe watery diarrhea from 10 to 15 stools a day

-lower abdominal pain with cramping and fever.

-Symptoms usually appear within 5 to 10 days after initiation of antibiotics.

-Cause: long term antibiotic use:
Clindamycin & Fluroquinolones

Tx:
-DC whatever antibiotic we were using

-Start vancomycin

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13
Q

Colon Cancer

A

-Very gradual (years) with vague gastrointestinal (GI) symptoms.
-Tumor may bleed intermittently, and patient may have iron-deficiency anemia.
-***ribbon shaped or thin pencil stools
-Heme-positive stool, dark tarry stool, and mass on abdominal palpation.
-The U.S. Preventive Services Task Force (USPSTF) recommends screening for colon cancer between ages of 50 and 75 years (Grade A recommendation).

Where do most polyps occur? – Descending colon

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14
Q

Crohn’s Disease

A

CD is an IBD that may affect any/ALL part(s) of the GI tract, from mouth (canker sores), small or large intestine, rectum, and anus.

  • periumbilical to RLQ abdominal pain occur.

-***Fistula formation and anal disease occur only with CD (not UC).

-May palpate tender abdominal mass. Remissions and relapses are common.

-Higher risk of toxic megacolon and colon cancer.

-Risk of development of lymphoma is also increased, especially for patients treated with azathioprine.

-More common in Ashkenazi Jews.

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15
Q

Colitis

________(hematochezia) more common with UC than with CD.

Severe “___ ______” located on the ________ side of the body
exacerbated by ________

A

IBD that affects the colon/rectum.

-***Bloody diarrhea with mucus (hematochezia) more common with UC than with CD.

-Severe “squeezing” cramping pain located on the left side of the abdomen with bloating and gas that is exacerbated by food.

-Accompanied by arthralgias and arthritis (15%–40%) that affect large joints, sacrum, and ankylosing spondylitis.

-May have iron-deficiency anemia or anemia of chronic disease.

-Higher risk of toxic megacolon and colon cancer.

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16
Q

Zollinger–Ellison Syndrome

A

A gastrinoma located on the pancreas or the stomach; secretes gastrin, which stimulates high levels of acid production in the stomach.

-The end result is the development of multiple and severe ulcers in the stomach and duodenum.

-Complaints of epigastric to midabdominal pain.

-Stools may be a tarry color.

-Screening by serum fasting gastrin level.

-Refer to gastroenterologist.

The nurse practitioner reviews the results of a serum fasting gastrin level and finds there is no inhibition of gastrin levels. Which diagnosis is most likely?
— Zollinger–Ellison syndrome is a neuroendocrine tumor that leads to gastrin hypersecretion and multiple peptic ulcer formation. These tumors, called gastrinomas, secrete large amounts of the hormone gastrin, which causes the stomach to produce too

“feeling ILL due to all the acid!”

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17
Q

Carnett’s Test

A

An abdominal maneuver that is used to determine if abdominal pain is from inside the abdomen or if it is located on the abdominal wall.

-Patient is supine with arms crossed over their chest. Instruct patient to lift up shoulders from the table so that the abdominal muscles (rectus abdominus) tighten.

-If source of pain is the abdominal wall, it will increase the pain; if the source is inside the abdomen, the pain will improve.

“in CARNage doing these crunches”

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18
Q

worrisome symptoms in GERD

A

—e.g., odynophagia (pain with swallowing),
-dysphagia (difficulty swallowing),
-early satiety, weight loss,
-iron-deficiency anemia (blood loss)
-male >50 years
—refer to gastroenterologist.

Any patient with at least a decade or more history of chronic heartburn should be referred to a gastroenterologist for an endoscopy to rule out Barrett’s esophagus.
* Patients with Barrett’s esophagus have up to 30 times higher risk of cancer of the esophagus (adenocarcinoma type).

19
Q

Barrett’s esophagus is a

A

-precancer (esophageal cancer). Diagnosed by upper endoscopy with biopsy.

20
Q

Know lifestyle factors to teach patient

A
  • (e.g., no mints, avoid caffeine).
21
Q

Know Cullen’s sign

A

-(edema and bruising of the subcutaneous tissue around the umbilicus)

22
Q

Grey Turner’s sign

A

-(bruising/bluish discoloration of the flank area that may indicate retroperitoneal hemorrhage).

TURN the pt to see the discoloration on the pt’s flank

23
Q

Classic pain of acute pancreatitis is

Know how to perform Rovsing’s and Markle maneuvers. Positive tests mean

A

-severe midepigastric pain that radiates to midback. (pancreatitis typically LUQ)

-acute abdomen- appendicitis .

24
Q

If patient needs treatment for GERD, start with

A

-H2 antagonists; if poor relief or erosive esophagitis, step up to PPIs.

25
Q

Gastroenteritis

Most causes:

Symptoms:

Labs?

Tx:

A

-think of stomach flu-

Most causes:
-Viral (norovirus)

Symptoms:
-diarrhea / vomiting
- wt loss
-dehydration (especially in elderly)

Labs?
-urinalysis
-CBC/CMP
-Stool studies

Tx:
Maintain hydration status
-antiemetics
-anti-diarrheals
-BRAT diet (Bananas, Rice, Applesauce, Toast)

26
Q

Bacterial Gastroenteritis tx:

A

-fluoroquinolones
-macrolides

27
Q

“Protozoal Gastroenteritis”
aka:

Risk:

Tx?

Education:

A
  • “Giardia”

Risk: traveling
tx? – Flagyl
education: drink bottoed water/ avoid ice cubes/wash fruit & veggies etc.

28
Q

Antacids

Consider in elderly

A

-acid reflux relief
-Calcium Carbonate (TUMS)

Consider in elderly
-cause constipation ( Ca and aluminum)
-cause diarrhea (magnesium)

29
Q

Sucralfate (Carafate)

When should it be taken?

What is this used for?

A

-Duadenal Ulcers Tx

When should it be taken?
-Before meals

What is this used for?
-coats stomach lining to decreased irritation and help prevent ulcers

30
Q

Do not give antidiarrheal medications if patient has acute onset of bloody diarrhea, fever, abdominal pain, or pain that worsens with defecation because

A

-it may be caused by E. coli - May need to go to ED

31
Q

Anti-Nausea:

meds:

hint: rollercoaster

A

-Zofran
-Phenergan
-Stemetil

“Z(y)o!, lets have PHEN with STEME on the rollercoaster”

32
Q

Ondansetron (Zofran)
Used for:
When to reduce the dose
Risk for what cardiac complication

A

Used for: Nausea
When to reduce the dose:
-when pt. has depression
-when pt. has hepatic impairment

Risk for what cardiac complication:
QT prolongation

“ON DANS Ekg, it says he’s got a QT issue…. He’s pretty depressed about it”

33
Q

Prochlorperazine (Stemetil)

Used for:

SE:

Too much can cause:

A

Used for: Nausea/Vomiting
SE:
-sedation
-anticholinergic effects

Too much can cause:
-Extrapyramidal reaction: tardive dyskinesia/acute dystonia
“STEME is in this PRO CHiOR, but im falling asleep! I cant wait till I can go to the bathroom just to get away…. then all of a sudden they all started freaking out!!”

34
Q

Promethazine (Phenergan)

A

Black box warning:
SEDATING
-causes respiratory depression in kids < 2yo.
“I need some METH at PROM to have PHEN… im that tired”

35
Q

Lactulose (Kristalose)

A

Osmotic Laxative

Good for:
-constipation
-Cirrhosis pts

How to know if med is effective?
-NOT BM #
-**If consciousness improves and Ammonia decreases

“LACT- LOSE- Let lose!! lose asshole- This tx’s your constipation Cirr. you need to decrease the amount of ammonia you’re taking in

36
Q

Loperamide (Imodium)

how does it work?

dose?

when to come in?

A

-OTC Diarrhea tx
-slows GI tract (NO pain relief)

Dosed:
Loading does is 2X normal, then take PRN
Pt education:
-S/S for > 3 days/ blood in stool? – you need to come in and be assessed

37
Q

Diphenoxylate/ Atropine (Lomotil)

Used for:

Is this a controlled substance?

A

Used for:
Diarrhea pain and symptom relief

Is this a controlled substance?
Yes. Diphenoxylate is an opioid (schedule V)
-slows contractions in the intestines

38
Q

Chvostek Sign:

Tests for hypocalcemia (typical post-thyroidectomy)
+ if:

A

Tap pts. Face- causes twitching of facial muscles “scrunched up”
-risk for seizure

39
Q

Trousseau Sign:

Tests for hypocalcemia (typical post-thyroidectomy)
+ if:

A

Involuntary contraction in hand and wrist after compression of blood pressure cuff
-risk for seizure.

Ultrasounds always ordered for:
-cholecystitis
-kidney stones
-abd. Aneurism

40
Q

Treatment for H. pylori–Negative Ulcers

Treatment for H. pylori–Positive Ulcers

A

Treatment for H. pylori–Negative Ulcers
-Stop use of NSAIDs. If a patient needs long-term NSAIDs, ulcer formation risk can be decreased if combined with a PPI or misoprostol.
* Encourage smoking cessation. Stop drinking alcohol.
* Combine lifestyle changes with PPIs or H2 antagonists (no antibiotics).

Treatment for H. pylori–Positive Ulcers
Triple therapy:
Quadruple therapy:

41
Q

Exam Tips
* Determine whether question is about H. pylori–negative ulcers or H. pylori–positive ulcers.

  • H. pylori–positive ulcers require antibiotics for ________________
  • Worrisome symptoms for esophageal cancer include ______________
A

14 days plus PPI orally twice a day.

anorexia, early satiety, anemia, recurrent vomiting, hematemesis, and weight loss.

42
Q

Clinical Pearls
* Recurrence rate for untreated PUD is ______
* High rates of clarithromycin resistance (42%) in the United States. Avoid using clarithromycin therapy if __________
* PPIs cure ulcers faster than _________
* \Handwashing with soap and water is more effective against C. difficile than__________

A

-about 60%.

-there is high resistance in your area.

-H2 antagonists

  • alcohol-based hand wipes
43
Q

Exam Tips

  • PCR tests are not antibody tests. They test for presence of viral RNA. A positive result means that ______________
  • Hepatitis C has highest risk of __________
  • Screening test for hepatitis C virus is called _________. If positive, next step is to order ______. If positive, patient has ___________
  • GGT is elevated in liver disease and biliary obstruction. A “lone” elevation in the GGT is a sensitive indicator ________
  • Alkaline phosphatase (ALP) is normally elevated during the teen years due to bone growth. The ALP may also be elevated in bone disorders such as ________________
  • A person must have hepatitis B to become infected with _______. There is no vaccine for that, but hepatitis B vaccination will prevent acquisition of _______.
    *______ is more sensitive to liver damage than ____.
  • For mild cases of GERD, _________. For moderate-to-severe ____________.
  • Acute pancreatitis symptoms: _______________
A

-the virus is present. This test can be performed for diagnosing disease such as hepatitis C or HIV.

-cirrhosis and liver cancer.

-the HCV antibody (anti-HCV)
-HCV RNA test
-hepatitis C.

-of possible alcoholism.

-vitamin D deficiency, Paget’s disease, and bone cancer. A GGT, which would be elevated with liver disease, may be drawn to differentiate between liver disease and bone disorders.

-hepatitis D

-ALT is more sensitive to liver damage than AST
AST is also found in other organs such as the heart and skeletal system. AST and ALT may be elevated and may reflect acute liver injury or inflammation. However, these levels may be normal in chronic liver disease, such as cirrhosis.

-lifestyle management and antacids or H2 antagonists.
-esophagitis, first line is PPIs.

-Amylase and lipase are sensitive tests used for pancreatic inflammation (pancreatitis).

Normal Amylase: 23–85 U/L (some lab results go up to 140 U/L)

Normal Lipase: 0–160 U/L

Pancreatitis suspected: both> 200 U/L > 200 U/L