Gastro

Question 1

treatment for mild/mod C Diff

Answer 1

oral metro

Question 2

test results for PBC

Answer 2

raised ALP and raised antimitochondrial antibodies

Question 3

histology of pbc

Answer 3

granulomas present

Question 4

Bile duct condition associated with IBD

Answer 4

Primary Sclerosing Cholangitis = 80% have IBD

affects bile ducts inside and outside liver

Question 5

what affects the intrahepatic bile ducts? (not outside)

Answer 5

Primary Biliary Cholangitis

Question 6

test most indicative of liver function?

Answer 6

Prothrombin time / INR

‘synthetic function’

Question 7

management of H Pylori Negative Peptic Ulcer?

Answer 7

4-8 weeks of full dose PPI

Question 8

where is Vitamin B12 absorbed?

Answer 8

Terminal Ileum

Question 9

courvoisier’s sign

Answer 9

painless palpable gallbladder and jaundice

Pancreatic cancer

Question 10

treatment for cerebral oedema

Answer 10

IV Mannitol (mechanism - unknown)

Question 11

rare disease involves trouble swallowing, iron deficiency anaemia, glossitis, and cheilosis?

Answer 11

Plummer-Vinson Syndrome

Question 12

management of oesophageal high grade dysplasia?

Answer 12

Endoscopic ablation

Question 13

management of oesophageal low-grade dysplasia?

Answer 13

High dose PPI + 6 monthly endoscopic surveillance

Question 14

triple therapy for H Pylori?

Answer 14

Amoxicillin (metro), Clarithromycin, Omeprazole for 7 days

Question 15

first line treatment for ascites?

Answer 15

spironolactone (2nd line furosemide)

Question 16

which pathology is most asscoiated with H Pylori?

Answer 16

Duodenal Ulcer

Question 17

what presents with a classic triad of abdo pain, ascites and liver enlargement?

Answer 17

Budd Chiari Syndrome

caused by occlusion of hepatic veins that drain the liver

Question 18

examples of drug induced dyspepsia?

Answer 18

bisphosphonates
NSAIDs
CCBs
Steroids
nitrates
theophyllines
Macrolide antibiotics

Question 19

management of Campylobacter?

Answer 19

mild/mod - supportive

Severe- erythromycin

Question 20

cancer in oesophagus with hoarse voice think…

Answer 20

upper 1/3 associated with smoking SCC

Question 21

common site for adenocarcinoma in oesophagus?

Answer 21

lower 1/3 (arises from gladnular cells)

Question 22

most senstive tool for diagnosis and staging of pancreatic cancer?

Answer 22

endoscopic US

Question 23

management of EBV?

Answer 23

patients present with glandular fever, headache, deranged LFTs

Supportive
Amoxicillin may lead to widespread rash

Question 24

major haemorrhage in warfarin patient?

Answer 24

give prothrombin complex concentrate (contains factors II,VII, IX, X)
instant acting Vit K takes 6-8 hours!!

Question 25

tumour marker in cholangiocarcinoma and pancreatic cancer?

Answer 25

CA 19-9

Question 26

which electrolyte are we concerned about in acute pancreatitis?

Answer 26

Hypocalcaemia.

Question 27

drug for Crohn’s?

and what interaction do you need to be aware of?

Answer 27

Azathioprine

interacts with allopurinol - bone marrow suppression

Question 28

tender hepatomegaly, ascites and sudden onset abdo pain suggests?

Answer 28

budd chiari syndrome