Derm Flashcards
patient has dermatomyositis, what else should be investigated for?
Malignancy - can be a paraneoplastic phenomenon
which MHC antigen is psoriasis related to?
HLA-B27
treatment for fungal nail infection?
oral terbinafine
treatment of psoriasis?
1st line avoid irritants + soap substitutes + emollients (diprobase)
2nd line - topical vit D (calcipitriol) + steroids
3rd line - phototherapy/ oral methotrexate, ciclosporin etc
4th line - biologics - anti TNFs
what initially presents as a small patch (herald) with a later widespread rash containing multiple patches? Usually occurs after URTI?
Pityriasis Rosea
Treatment = self limiting (disappears after couple of weeks)
causes of erythroderma?
Eczema, Psoriasis, drug-induced
Admit, give IV fluids, watch for fluid loss, electrolytes and hypothermia
purple and itchy plaques and lace-like pattern in mouth (stings while eating)
Lichen Planus (ithcy purple - planus)
pemphigus vulgarus vs pemphigoid
vulgarus - blisters tend to be burst (IgG within epidermis)
pemphigoid - blisters intact due to deepness (IgG on basement membrane)
bacteria involved in acne?
propionibacterium acnes
treatment of acne?
stepwise:
- topical benzoyl peroxide
- tetracycline
- vit A analogue
- COCP
- oral isotretinoin
If scarring present then give Oral Isotretinoin
slow growing lesion, hx of sun burn, rolled edges (pearlescent?), telangectasia
Basal cell carcinoma - don’t metastasise
- excision with 4 mm margins
- MOH’s micrographic surgery in ‘delicate’ areas
> 1mm breslow thickness, what do we do?
sentinel node biopsy! (more likely nodal involvement of melanoma)
what is a melanoma? how to treat?
cancerous growth of melanocytes (reduce sun exposure)
2 week referral to derm.
wide local excision + lymphadenectomy
+/- adjuvant radiotherapy
causes and how to deal with steven johnsons syndrome?
drug eruption (often a week after) -erythematous macules > target lesions
Can progress to TEN if >30% body surface
Supportive therapy with skin and eye care
history of eczema then presents with widespread rash think…
eczema herpeticum (treat with IV aciclovir)
what rash (light red scaly marks) usually appears few weeks after strep throat infection?
Guttate Psoriasis
