gastro 18/19 Flashcards
what are some manifestations of GI dysfunction?
anorexia nausea vomiting (projectile) Abdominal pain changes is bowel sounds constipation diarrhea GI bleeding (upper and lower) Jaundice
what does black tarry feces indicate?
melena: distinctive, fowl odor
- seen when bleeding is in duodenum, through small bowel and large bowel, profuse amount of bleeding
- some cancers can cause this
what is jaundice?
- caused by increased amount of bilirubin
- yellow discoloration of skin, mucous membranes, sclerae
- will see this when there is liver failure, gallstones, and excessive breakdown is RBS (hemolytic newborn, sickle cell, transfusion reaction)
what is obesity associated with?
the first leading cause of death
what is central obesity?
- the abdomen
- visceral fat that surrounds organs
- abdominal obesity =higher risk of disease and illness compared to ppl who have fat around hips. abdominal is dangerous because it is deeper and sounds organs
risk factors associated with obesity?
- atherosclerosis, cardiovascular disease, diabetic (2) and cancer
- is linked to hypertension and stroke
what are two congenital structure anomalies in children?
prevalence?
-esophageal atresia
-tracheoesophageal fistula
one in ever 3000 births
what is esophageal atresia?
- means there is a dead end, something that should carry through that stops
- condition in which the esophagus end in a blind punch that does connect with the stomach, it just ends
what is tracheoesophageal fistula?
- connects between two structures that should not connect
- abnormal connection between the trachea and the esophagus
- abdominal fetal development around 6 weeks- when spilt is supposed to happen)
risk factors for congenital structure anomalies in children
- sometimes happens without reason
- alcohol, smoking, diabetes, older maternal age, mom exposed to infectious disease, exposure to insecticides
manifestations of esophageal atresia and tracheoesophageal fistula?
-excessive drooling (does get passed down to GI system)
vomiting after meal
choking, coughing (food going into lungs)
-milk return through mouth and nose
abdominal distention
cyanosis
aspiration of stomach contents
complications of esophageal atresia and tracheoesophageal fistula?
- failure to gain weight
- repetitive pneumonia -lung infections
- requires surgical repair after birth
what are the two gastrointestinal obstructions?
-functional obstruction: more usual, loss of function, paralysis of tube, ends up having same result If something was physically blocking tube
-mechanical obstruction: structures, physical things that block something passing through a tube
both = obstructed tube
result of GI obstruction?
- area above obstruction distends, is ischemic, gas and fluid accumulation
- loss of function below, distension above obstruction
- compresses and squeezed blood vessel of lumen of gut and can lead to ischemia and necrosis of gut
what are some examples of functional obstruction?
1) paralytic ileus: paralyzed ileum. occurs after bowel surgery, caused absent bowel sounds
leakage of bail can also cause this
2) Hirschsprung disease: will require surgery
- congenital- born with defective rest and digest NS
- aganglionic: absence of ganglion to bowel, altered NS
- Megacolon (means big colon, due ot lacking PNS, causes distended abdomen).
what are some examples of Mechanical obstruction?
- pyloric stenosis
- Volvulus (twisted bowel)
- Intussusception
- hernias
- impacted feces
- tumors
- most will require surgery
what is Volvulus
(twisted bowel)
what is pyloric stenosis
- narrowing of pyrosis stenosis
- this is the opening into the intestine after the stomach
what is Intussusception
small bowel goes into colon and then folds back
symptoms of bowel obstructions?
- regardless of cause:
- nausea and vomiting
- cramping abdomen (colicky)
- distension
- dehydration
- perforation
- necrosis
- sepsis - dead bowel = HIGH risk of infecc
what does neoplasia of the GI tract include?
cancer at any location:
- esophagus
- stomach
- colon and rectum
- gallbladder
- pancreas
- liver
incidence of colon cancer?
common in developed counties
- second leading cause of death by cancer in men
- is more common in men
- third leading cause of cancer in women
risk factors for colon cancer?
the longer we live, the more mutations we have, the higher the risk -increases with age -heredity diet (high fat low fiber) -smoking obesity high alcohol consumption ulcerative colitis
mortality rate for colon cancer?
5 year survival is around 90% if found early
on average: 70-90%
manifestations of colon cancer?
- pain in most locations
- changes in bowel habits (poos are skinner- passing obstruction)
- blood in poo
- anemia
- rectal discomfort and pain
- regardless of cancer: main manifestations are fatigue
tx of colon cancer?
surgical resection
surgical removal
chemotherapy
cancer of the pancreas incidence?
increases with age
cancer of pancreas mortality rate?
almost 100%
-diagnosis are often too late