Gastro Flashcards
What is GORD?
Involuntary passage of food into oesophagus, extremely common in infancy
What causes GORD in paediatrics?
Inappropriate relaxation of LOS due to immaturity
What are some symptoms of GORD in paeds?
Recurrent regurgitation and vomiting
Sufficient weight gain
Frequent mess, smel land change of clothes
What are some risk factors for developing GORD in paeds?
Children with Cerebral Palsy/Other neurodevelopmental disorders
Preterm infants
Following surgery for oesophageal atresia/diaphragmatic hernia
What are some investigations that may be used for suspected GORD?
24 hour oesophageal pH monitoring to quantify
Endoscopy and Biopsy if ?Oesophagitis/other cause
How can GORD be managed?
Uncomplicated - Parental reassurance, thickening agents
Significant - Ranitidine/Omeprazole
Nissen Fundoplication if unresponsive to medical therapy
What is Coeliac disease?
Gliadan factor of Gluten and Wheat provokes an immune response in the small bowel, giving shortening of intestinal Villi
How does Coeliac disease present in children?
Malabsorption issues at 8-24m after introducing wheat foods Faltering growth Abdominal distension Buttock wasting Abnormal stools General irritability
What are some risk factors for developing Coeliac disease?
T1DM
Autoimmune Thyroid disease
Hx in a first degree relative
What are some symptoms of Coeliac disease?
Mild non-specific GI symptoms
Anaemia
Faltering growth
How is Coeliac disease in children diagnosed?
Screen for IgA anti-tTG antibodies
Duodenal biopsy
How is confirmed Coeliac disease managed?
Gluten free diet for life
What are some risks of continuing a Gluten diet in Coeliac disease?
Micronutrient deficiency
Bowel Malignancy - Small Bowel Lymphoma
What is Biliary Atresia?
A congenital condition where a section of the bile duct is narrowed/absent giving cholestasis of bile
How does Biliary Atresia present?
Shortly after birth with significant persistent jaundice due to high conjugated bilirubin
