Gastric Secretions and Cells Flashcards
Secretes mucous
Mucous neck cells
Components of mucous
Mucin
Electrolytes
Phospholipids
Water
Secretes HCL and IF
Parietal cells
Stimulates release of HCl from parietal cells
Gastrin
ACh
Histamine
Inhibits release of HCl from parietal cells
Somatostatin
Synthesize pepsinogen and gastric lipase
Chief cells
Stimulates pepsinogen secretion
ACh
HCl
Activates pepsinogen
HCl
Pepsin
–Cleaves peptide bonds of denatured proteins
Synthesize histamine
ECL cells
Stimulates histamine secretion
Gastrin
Inhibits histamine secretion
Somatostatin
Synthesize somatostatin
D Cells
Stimulates somatostatin secretion
HCl and Gastrin
Inhibits somatostatin secretion
ACh
Synthesize gastrin
G Cells
Stimulates gastrin secretion
GRP (gastrin releasing peptide)
Inhibits gastrin secretion
Somatostatin