Gastric Neoplasia I (Gupta/Jackson) Flashcards by Barrett Thompson

Q

What is this?

A

Hyperplastic Gastric Polyp (don’t think there is any way to tell grossly what type of polyp it is)

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Q

What is this?

A

Fundic Gland Gastric Polyps

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Q

What is this?

A

Gastric Adenoma

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Q

What is shown here?

A

Narrowing of the gastric outlet - due to carcinoma

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Q

What is shown in images A and B?

A

A - maligant ulceration - while you can’t know for sure with out biopsy the heaped up edges suggest malignancy

B - Simple Gastric Ulcer - punched out appearance lowers the risk of it being malignant

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Q

What symptoms might this patient be experiencing from this giant ulcer that is probably malingnat?

A

Anemia

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Q

A

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Q

What is the most likely cause of the pathology shown on the right?

A

Linnitus Plastica - from diffuse gastric adenocarcinoma

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Q

What is shown here?

A

NL gastric mucosa

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Q

What is shown in this biospy taken from a lesion in the stomach?
• Key histologic features?

A

HYPERPLASTIC GASTRIC POLYP
• Also notice mucinous looking cells that are lining the polyp

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Q

What gastric pathology is seen here?
• Key features?

A

Fundic Gland Gastric Polyp

Key Features:
• Cystic Spaces lined with Parietal and Chief cells

(contrast this to the mucinous appearing lining of hyperplastic polyps)

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Q

What is shown on the left and right here?

A

Left: Adenomatous polyp with High N/C, Hyperchromasia, CIgar Shaped nuclei, and fairly NL architecture with few mitotic figures

Right: Normal Tissue

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Q

What gastric pathology is seen on the left and right here?

A

Left: Adenomatous polyp that has higher N/C, Hyperchromasia, Cigar Shaped nuclei

Right: HIGH GRADE adenomatous polyp, characterized by: Budding, Cribiforming, and Architectural Distortion

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Q

A

Gastric Adenocarcinoma

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Q

What type of gastric adenocarcinoma is this?

A

Diffuse Type - Characterized by SIGNET RING CELLS that appear similar to macrophages

**Gross picture shown below

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Q

Invasion

A

Invasion

Q

What is the arrow on the right pointing to?

A

Intestinal Metaplasia

Q

Menetrier Disease
• Age
• Location
• Cell Type
• Inflammation

A

Q

Menetrier Disease
• Symptoms
• Risk Factors
• Association with Adenocarcinoma

A

Q

ZE syndrome
• Age
• Location
• Cell Type
• Inflammation

A

Q

ZE syndrome
• Symptoms
• Risk Factors
• Association with Adenocarcinoma

A

Q

Hyperplastic Polyp
• Age
• Location
• Cell Type
• Inflammation

A

Q

Hyperplastic Polyp
• Symptoms
• Risk Factors
• Association with Adenocarcinoma

A

Q

Fundic Gland Polyp
• Age
• Location
• Cell Type
• Inflammation

A

Q

Fundic Gland Polyp
• Symptoms
• Risk Factors
• Association with Adenocarcinoma

A

Q

Gastric Adenoma
• Age
• Location
• Cell Type
• Inflammation

A

Q

Gastric Adenoma
• Symptoms
• Risk Factors
• Association with Adenocarcinoma

A