Gastric cancer Flashcards
1
Q
Define:
A
Cancer of the stomach. Usually adenocarcinoma but can be:
Lymphoma
Leiomysarcoma
Stroma, tumours
2
Q
Aetiology:
A
Unknown
Genetic and environmental factors
3
Q
Risk factors
A
Smoked and processed food - high in salt and nitrates Blood group A H. Pylori Alcohol Smoking Gastric polyps Partial gastroectomy Strophic gastritis Pernicious anaemia
4
Q
Epidemiology
A
Common cause of cancer death
Highest incidence is in Japan
6th most common cancer in the UK
Presents at over 50
5
Q
Symptoms
A
Asymp early Early satiety Epigastric discomfort Haematemesis, Malena Weight loss Anorexia Nausea/vomiting Dysphagia Metastasis (Ascites and jaundice)
6
Q
Signs:
A
May be Normal
Epigastric mass
Virchow node - trossier’s sigh
Sister Mary Joseph Nodule (metastatic nodule at umbilicus)
Kruskenbergs tumour (ovarian metastasis)
Signs of anaemia
Abdo tenderness
Ascites
7
Q
Investigations
A
Upper GI endoscopy - biopsy ulcers
Bloods - FBC (anaemia) , LFTs
Endoscopic USS to see lymph node involvement and depth of invasion
Liver US and bone - staging
Laparoscopy to see tumour resection
