Fusobacterium and Bacteriodes Flashcards
What type of bacteria are Fusobacterium and Bacteroides?
Non-sporeforming, anaerobic bacteria
What are the 3 morphological groups of non-sporeforming anaerobes?
Gram-negative bacilli
Gram-positive cocci
Gram-positive bacilli
Where are these anaerobes normally found?
Mucous membranes and intestinal tract
What percentage of gut flora do Gram-negative anaerobic bacilli constitute?
> 90% of intestinal bacteria
What types of infections do Fusobacterium and Bacteriodes
cause?
Abscesses, necrotic, and suppurative processes
Fusobacterium and Bacteriodes typically infect alone or with other bacteria?
Often mixed infections with aerobes/facultative anaerobes
Fusobacterium produces endospores. (T/F)
False (non-sporeforming)
Fusobacterium and Bacteriodes require oxygen for growth. (T/F)
False (strict anaerobes)
Gram-negative anaerobes aid in cellulose digestion. (T/F)
True
Pure anaerobic infections are most common. (T/F)
False (usually polymicrobial)
What family do most pathogenic anaerobic Gram-negative bacilli belong to?
Bacteroidaceae
Which clinically important group of Gram-Negative Anaerobic Bacilli contains 10 species?
Bacteroides fragilis group
What is the current name of the former Bacteroides corrodens?
Eikenella corrodens
Which reclassified species causes summer mastitis in cattle?
Porphyromonas levii (formerly B. levii)
What organism causes contagious foot rot in sheep?
Dichelobacter nodosus
What transmission routes are common for these anaerobes?
Feco-oral and oral-oral
Which species is associated with oral infections in horses/cats?
Prevotella heparinolyticus
What are the two pathogenic subspecies of Fusobacterium necrophorum?
subsp. necrophorum
subsp. funduliforme
To which family does Dichelobacter nodosus (cause of ovine foot rot) now belong?
Cardiobacteriaceae (formerly classified under Bacteroides)
What is the primary disease caused by this Gram-negative anaerobic bacillus?
Contagious foot rot in sheep
What is the current name of the Gram-negative anaerobic bacillus formerly called Bacteroides melaninogenica?
Prevotella melaninogenica
What is the current family classification for Fusobacterium species?
Fusobacteriaceae
How frequently does Fusobacterium nucleatum infect animals compared to other species?
Infrequent (unlike F. necrophorum)
What are the two main genera of Gram-positive anaerobic cocci?
Peptostreptococcus and Peptococcus
Where are these anaerobic cocci normally found?
As normal flora on mucous membranes.
Which species is the type species of Peptostreptococcus?
Peptostreptococcus anaerobius
What is the current name of Peptostreptococcus magnus?
Finegoldia magna
How many Peptococcus species exist, and what is its name?
Only one species: Peptococcus niger
Which anaerobic bacillus causes swine cystitis/pyelonephritis?
Actinobaculum suis (formerly Eubacterium suis)
Where is A. suis harbored in boars?
Preputial diverticulum (transmitted during breeding)
Is Lactobacillus pathogenic in animals?
No - normal genital tract flora
What human condition is Propionibacterium associated with?
Acne (non-pathogenic in animals)
What three systems create anaerobic conditions?
Anaerobic jars (GasPak)
Glove boxes
Pre-reduced media (thioglycolate broth)
What diagnostic test identifies anaerobic metabolites?
Gas-liquid chromatography of fatty acids
Why must Gram-positive Anaerobic specimens avoid oxygen exposure?
O₂ kills strict anaerobes
What are the two pathogenic subspecies of Fusobacterium necrophorum?
Fusobacterium necrophorum subsp. necrophorum (more virulent)
Fusobacterium necrophorum subsp. funduliforme
What two key toxins does Fusobacterium necrophorum produce?
Endotoxin
Leukotoxin
Why are capsulated strains of Fusobacterium necrophorum more dangerous?
They show increased virulence in mice
What two major conditions does Fusobacterium necrophorum cause in cattle?
Liver abscesses
Foot rot
What viral disease does Fusobacterium necrophorum complicate in sheep?
Ulcerative dermatosis (as secondary infection)
What nasal condition does Fusobacterium necrophorum cause in swine from boar injuries?
“Bull nose”
Which Bacteroides species is essential for transmitting foot-rot in sheep?
Bacteroides nodosus
What are the growth requirements of Bacteroides nodosus?
Obligate anaerobe