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Micro Final > Fungi causing internal (systemic) mycoses > Flashcards

Fungi causing internal (systemic) mycoses Flashcards

1
Q

__________ is the most common fungal cause of systemic infection

A

Aspergillus fumigatus

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2
Q

T/F isolation of A. fumigatus is sufficient evidence of infection

A

False. need to see organism in the lesion or have repeat isolation

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3
Q

In cattle aspergillus causes:

A

pulmonary and cutaneous infection, abortions, rumenitis, gastritis, mastitis

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4
Q

In horses aspergillus is associated with:

A

abortion, guttural pouch infection, diarrhea in foals

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5
Q

In dogs __________ is assocated with aspergillus

A

frontal sinus infection

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6
Q

Asperigillus causes __________ in cats

A

pulmonary disease

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7
Q

__________ is the cause of respiratory disease in captive penguins and brooder pneumonia

A

Aspergillus

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8
Q

__________ causes crop mycosis in commercial turkey flocks

A

aspergillus

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9
Q

How is aspergillus transmitted

A

usually via feed in commercial poultry

inhalation/ingestion of spores are major routes

animals must common incontact with large numbers of spores are be immunocompromised to exhibit disease

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10
Q

__________ __________ has a predelection for the brain and meninges, neurotrpic fungus

A

Cryptococcus neoformans

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11
Q

Cryptococcus neoformans is associated with __________ (habitat)

A

dessicated pigeon feces

associated with trees w/ pockets of rotted material

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12
Q

__________ __________ fungus in cattle may infect mammary tissue and adjacent LN

A

Crytococcus neoformans

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13
Q

__________ __________ in horses causes nasal discharge, respiratory distress due to nasal granuloma fomraiton

A

Cryptococcus neoformans

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14
Q

__________ examination for thick capsule in very important for C. neoformans

A

India Ink

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15
Q

__________ lserodiagnosis detects antigen or serum CSF to C. neoformans

A

latex slide agglutination

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16
Q

__________ __________ is the cause of North American blastomycosis, a chronic granumlomatous and suppurative infection of humans and domestic animals

A

Blastomyces dermatitidis

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17
Q

__________ __________ is a saprophyte important in the Ohio, Missouri, and Mississippi River valleys

A

Balstomyces dermatidis

18
Q

Blastomyces dermatidis is transmitted via:

A

inhalation of spores

19
Q

T/F the pulmonary form of Blastomyces dermatidis disseminates via hematogenous route and produces granulomatous infection of skin and internal organs

A

True

20
Q

__________ __________ causes valley fever and chronic disseminated granulomatous lesions

A

Coccidiodes immitis

21
Q

__________ __________ produces hyphae that are readily aerosolized and very dangerous for lab workers

A

Coccidiodes immitis

22
Q

__________ __________ is edemic to the desert country of the SW USA and San Joaquin Valley of California

A

Coccidiodes immitis

23
Q

C. immitis causes __________ in cattle

A

benign disease of the LN of the chest

24
Q

C. immitis causes __________ in dogs

A

granulomatous lesions w/ lungs as primary site, disseminates and has chronic course with debilitation and death

25
Q

C. immitis causes __________ in humans

A

Valley fever, pulmonary form, may disseminate, occasionally skin lesions are primary site

26
Q

__________ is used to treat C. immitis infections

A

Amphotericin B

27
Q

T/F Cattle are the most common domestic animal affected by Coccidiodes immiis

A

FALSE its dogs

28
Q

__________ __________ produces a generalized disease involving the reticulo-endothelial system

A

Histoplasma capsulatum

29
Q

__________ and __________ are the two kinds of spores observed with Histoplasma capsulatum

A

Microconidia

Tuberculate chlamydospores

30
Q

inhalation of spores which are then phagocytized and soread to the RES via __________

A

mononuclear cells

31
Q

__________ __________ us the cayse of epizootic lymphangitis or African farcy in horses and mules

A

Histoplasma capsulatum var farciminosum

32
Q

__________ is and endemic soil saphrophyte in parts of africa

A

Histoplasma capsulatum var farciminosum

33
Q

__________ may be used to treat Histoplasma capsulatum var farciminosum

A

Na Iodide

34
Q

__________ is a general term used to describe infections caused by zygomycetesm often take the form of granulomatous and ulcerative lesions, frequently in the lymphnodes and respiratory and alimentary tracts

A

Zygomycosis

35
Q

What are the 3 genera of Zygomycosis and whar is special about them morphologically?

A

Mucor, Rhizopus, Absidia

see coarse, non septate, branching hyphae w/ rounded sporangia

when observed on LPCB mounts in culture they all have sporangium attached to sporangiophore

36
Q

__________ is a subcutaneous infection caused bu a number if dermatiaceous fungi, reported from dogs, horses and humans

A

CHromomycosis

37
Q

What species are involved in chromomycosis?

A

Hormodendrum, Cladosporium, are most common

38
Q

Pathogenesis of chromomycosis?

A

infection via wounds/abrasions, nodular, frequently ulcerative lesions of thef eet and legs w/ regional granulomatous lymphandenitis

39
Q

__________ is a localized swollen lesion consisting of granulomas and abcesses which suppurate and drain through sinus tracts, usually involve skin, sub q, fascia and bone

A

Mycetoma

40
Q

__________ __________ caused by species of the genus Actinomyces

A

Actinomycotic mycetomas

41
Q

__________ __________ is caused bt atleast 13 different species of fungi reported infrequently from animals

A

Eumycotic mycetomas

42
Q

__________ , __________ and __________ are organisms that cause mycetomas

A

Allescheria, Curvualria, Helminthisporium

Micro Final (14 decks)

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