Fungi causing internal (systemic) mycoses Flashcards
__________ is the most common fungal cause of systemic infection
Aspergillus fumigatus
T/F isolation of A. fumigatus is sufficient evidence of infection
False. need to see organism in the lesion or have repeat isolation
In cattle aspergillus causes:
pulmonary and cutaneous infection, abortions, rumenitis, gastritis, mastitis
In horses aspergillus is associated with:
abortion, guttural pouch infection, diarrhea in foals
In dogs __________ is assocated with aspergillus
frontal sinus infection
Asperigillus causes __________ in cats
pulmonary disease
__________ is the cause of respiratory disease in captive penguins and brooder pneumonia
Aspergillus
__________ causes crop mycosis in commercial turkey flocks
aspergillus
How is aspergillus transmitted
usually via feed in commercial poultry
inhalation/ingestion of spores are major routes
animals must common incontact with large numbers of spores are be immunocompromised to exhibit disease
__________ __________ has a predelection for the brain and meninges, neurotrpic fungus
Cryptococcus neoformans
Cryptococcus neoformans is associated with __________ (habitat)
dessicated pigeon feces
associated with trees w/ pockets of rotted material
__________ __________ fungus in cattle may infect mammary tissue and adjacent LN
Crytococcus neoformans
__________ __________ in horses causes nasal discharge, respiratory distress due to nasal granuloma fomraiton
Cryptococcus neoformans
__________ examination for thick capsule in very important for C. neoformans
India Ink
__________ lserodiagnosis detects antigen or serum CSF to C. neoformans
latex slide agglutination
__________ __________ is the cause of North American blastomycosis, a chronic granumlomatous and suppurative infection of humans and domestic animals
Blastomyces dermatitidis
__________ __________ is a saprophyte important in the Ohio, Missouri, and Mississippi River valleys
Balstomyces dermatidis
Blastomyces dermatidis is transmitted via:
inhalation of spores
T/F the pulmonary form of Blastomyces dermatidis disseminates via hematogenous route and produces granulomatous infection of skin and internal organs
True
__________ __________ causes valley fever and chronic disseminated granulomatous lesions
Coccidiodes immitis
__________ __________ produces hyphae that are readily aerosolized and very dangerous for lab workers
Coccidiodes immitis
__________ __________ is edemic to the desert country of the SW USA and San Joaquin Valley of California
Coccidiodes immitis
C. immitis causes __________ in cattle
benign disease of the LN of the chest
C. immitis causes __________ in dogs
granulomatous lesions w/ lungs as primary site, disseminates and has chronic course with debilitation and death
C. immitis causes __________ in humans
Valley fever, pulmonary form, may disseminate, occasionally skin lesions are primary site
__________ is used to treat C. immitis infections
Amphotericin B
T/F Cattle are the most common domestic animal affected by Coccidiodes immiis
FALSE its dogs
__________ __________ produces a generalized disease involving the reticulo-endothelial system
Histoplasma capsulatum
__________ and __________ are the two kinds of spores observed with Histoplasma capsulatum
Microconidia
Tuberculate chlamydospores
inhalation of spores which are then phagocytized and soread to the RES via __________
mononuclear cells
__________ __________ us the cayse of epizootic lymphangitis or African farcy in horses and mules
Histoplasma capsulatum var farciminosum
__________ is and endemic soil saphrophyte in parts of africa
Histoplasma capsulatum var farciminosum
__________ may be used to treat Histoplasma capsulatum var farciminosum
Na Iodide
__________ is a general term used to describe infections caused by zygomycetesm often take the form of granulomatous and ulcerative lesions, frequently in the lymphnodes and respiratory and alimentary tracts
Zygomycosis
What are the 3 genera of Zygomycosis and whar is special about them morphologically?
Mucor, Rhizopus, Absidia
see coarse, non septate, branching hyphae w/ rounded sporangia
when observed on LPCB mounts in culture they all have sporangium attached to sporangiophore
__________ is a subcutaneous infection caused bu a number if dermatiaceous fungi, reported from dogs, horses and humans
CHromomycosis
What species are involved in chromomycosis?
Hormodendrum, Cladosporium, are most common
Pathogenesis of chromomycosis?
infection via wounds/abrasions, nodular, frequently ulcerative lesions of thef eet and legs w/ regional granulomatous lymphandenitis
__________ is a localized swollen lesion consisting of granulomas and abcesses which suppurate and drain through sinus tracts, usually involve skin, sub q, fascia and bone
Mycetoma
__________ __________ caused by species of the genus Actinomyces
Actinomycotic mycetomas
__________ __________ is caused bt atleast 13 different species of fungi reported infrequently from animals
Eumycotic mycetomas
__________ , __________ and __________ are organisms that cause mycetomas
Allescheria, Curvualria, Helminthisporium
