2009 Exam Flashcards
________________________________ is an organism that produces very little surface colony and appears as a zone of complete hemolysis that can be enhanced by removing a plug of agar under the colony
Brachyspira hyodysenteriae
________________________________ is the only rickettsial organism that multiplies in the intestinal epithelium of mammals
Neorickettsia risticii
________________________________ is the only dermatophyte that produces a metabolic byproduct that fluoresces when exposed to UV light
Microsporum canis
________________________________ is an obligate intramammary pathogen of cattle.
Streptococcus agalactiae
_____________________ is a term that denotes the ability of an organism to move through a viscous substrate such as mucus.
Viscotaxis
____________________ is the basic taxonomic unit used to identify the members of the genus Leptospira.
Serovariety
__________________________ is the site of primary multiplication of leptospires (first week of infection).
liver
_______________________ is the major clinical manifestation of leptospirosis in cattle
Abortion
___________ is the primary cell type infected by members of the genus Rickettsia.
Vascular endothelium
__________________ are produced by Fusarium roseum and F. tricinctum and primarily cause a Afeed-refusal syndrome
Tricothecenes
_____________________ is a heterotroph that can live on dead or decaying organic matter
Saprophyte
_______________________ is the Fc-receptor protein of Staphylococcus aureus
Protein A
______________________ is the name of a protein antigen that is of major importance in development of resistance to Group A streptococci
M-Protein
______________________ and __________________________ are the two Staphylococcus aureus enzymes that are most closely correlated with pathogenicity
Coagulase and DNase
_________________________________ is an organism that is harbored in the intestinal tracts of animals and causes mesenteric lymphadenitis and severe enterocolitis in humans that can sometimes mimic appendicitis.
Yersinia enterocolitica
______________________ is a bacterial genus that may be able to fuse with host cell membranes and thus exchange antigens with those membranes
Mycoplasma
________________________________ is the organism that commonly invades burn wounds and can ultimately cause the death of the patient.
Mycoplasma
_________________________________ is the organism that commonly invades burn wounds and can ultimately cause the death of the patient
Pseudomonas aeruginosa
_________________________________ is the cause of glanders in solipeds.
Burkholderia mallei
_________________________________ is the cause of melioidosis
Burkholderia pseudomallei
_________________________________ is the cause of columnaris disease of catfish.
Flavobacterium columnare
_________________________________ is the cause of coldwater disease of adult freshwater salmon and trout and rainbow trout fry syndrome
Flavobacterium psychrophilum
_____________________ is the name of the disease in water buffalo, bison and cattle that is caused by Pasteurella multocida types B and E
Hemorrhagic septicemia
_________________________________ has been associated with severe respiratory disease in adult cattle especially in the western U.S., respiratory disease in goats and septicemia in lambs
Bibersteinia trehalosi
_________________________________ is the cause of granulomatous, tumor-like lesions in the soft tissues of the head and neck of cattle
Actinobacillus lignieresii
_________________________________ is an organism that causes fatal, acute septicemia in 1- to 8-week-old pigs and is also recognized as a cause of arthritis, pneumonia and subcutaneous abscesses.
Actinobacillus suis
_________________________________ is a respiratory tract pathogen of cattle that produces LOS instead of LPS, has one or more Fc-receptor proteins and releases RNA components.
Histophilus somni
_________________________________ is the cause of rhinotracheitis or coryza in turkey poults.
Bordetella avium
___________________ is a clostridial toxin that blocks the release of glycine and gamma-aminobutyric acid at the level of the spinal cord and brainstem resulting in spastic paralysis.
Tetanospasmin
_________________________________ is the cause of blackleg in ruminants.
Clostridium chauvoei
_________________________________ is the cause of ulcerative colitis (quail disease) in birds
Clostridium colinum
_________________________________ is the cause of proliferative enteritis in pigs, foals, hamsters and possibly other animal species
Lawsonia intracellularis
What allows Clostridium botulinum to survive the processing of foods?
It forms spores which are resistant to heat
Why do we need to treat botulism with polyvalent antitoxin?
Because there are a number of serologically distinct toxins and the clinical signs are roughly the same
List the four major mycotoxins
Aflatoxin
ochratoxin
zearalenone
Ergot alkaloids
What is the method of action of Cholera Toxin?
Increases cAMP inside of target cells
What is the method of action of Edema Factor? (B.anthracis)
Increases cAMP inside of target cells
What is the method of action of Lekotoxin (M. hemolytica)
Forms pores in target cell membranes
What is the method of action of TSST1 (Staph aureus)
Acts as a superantigen
What is the method of action of Listeriolysin-O
Destabilizes and lyses the phagosomal membrane
What is the method of action of ApX1
Forms pores in target cell membranes
What is the method of action of LT toxin (E.coli)
Increases cAMP inside of target cells
What is the method of action of Edema Disease (E.coli)
Inhibits protein synthesis by NAD-dependent ADP-ribosylation of elongation factor 2.
What is the method of action of Streptolysin O
Destabilizes and lyses cell membranes by sequestering membrane cholesterol
What is the method of action of Phospholipase C
Hydrolyzes glycerophospholipids and sphingolipids in cell membranes
What is the method of action of Sulfonamides
Compete with para-aminobenzoic acid in folic acid synthesis
What is the method of action of 4-Fluoroquinolones
Inhibit DNA synthesis by inhibiting DNA gyrase A
What is the method of action of Penicillin
Bind to bacterial transpeptidases and block crossbridging in peptidoglycan
What is the method of action of Cephalosporins
Bind to bacterial transpeptidases and block crossbridging in peptidoglycan
What is the normal habitat of Erysipelothrix rhusiopathiae
. Intestinal tracts of swine, turkeys and many other animals
What is the normal habitat of Mycobacterium avium
Soil and intestinal tracts of birds
What is the normal habitat of Rhodococcus equi
Intestinal tracts of foals and soil
What is the normal habitat of Nocardia asteroides
Soil
What is the normal habitat of Listeria monocytogenes
Plant material and intestinal tracts of herbivores
What is the normal habitat of Mycoplasma bovoculi
Ocular mucosa of cattle.
What is the normal habitat of Corynebacterium pseudotuberculosis
Soil and skin of sheep and goats
What is the normal habitat of Dermatophilus congolensis
Soil
Bacteria that are most likely to be phagocytosed are:
a. Relatively hydrophobic
b. Relatively hydrophilic
c. Heavily encapsulated
d. Have a complex O-Antigen
e. Have a simple O-Antigen
Relatively hydrophobic
PPD tuberculins are usually preferred because:
a. Give fewer cross-reactions (are more specific) than other types of tuberculins.
b. They are more standardized than other types of tuberculins.
c. They have the extra benefit of immunizing those who are negative on the tuberculin tests.
d. Only a and b above.
e. Only b and c above
d. Only a and b above
a. Give fewer cross-reactions (are more specific) than other types of tuberculins.
b. They are more standardized than other types of tuberculins.
The virulence-associated protein A (VapA) is thought to be important in the immune response to:
a. Streptocococcus equi
b. Corynebacterium pseudotuberculosis var. Equi
c. Rhodococcus equi
d. Streptococcus suis
e. Erysipelothrix rhusiopathiae
c. Rhodococcus equi
In which of the following does Arcanobacterium pyogenes NOT play an important role?
a. Post-partum metritis in cattle
b. Foot-rot in cattle
c. Liver abscesses in feedlot cattle
d. Subcutaneous abscesses in cattle.
e. Chronic, abscessing mastitis in cattle
Liver abscesses in feedlot cattle
The commonly used modified-live vaccine used to immunize against Bacillus anthracis infection:
a. Lacks the genes for the capsule.
b. Lacks the genes for the PA antigen.
c. Lacks the genes for the EF antigen.
d. Lacks the genes for the LF antigen.
e. None of the above.
Lacks the genes for the capsule
Pathogenic members of the genus Leptospira are cleared from the blood 10 to 12 days following infection because:
a. The host generates a CMI response by that time and is able to kill the organisms.
b. The host generates an antibody response by that time and the antibody restricts the organisms to areas that are immunologically privileged.
c. The organism causes enough tissue damage by that time that defensins, lysozyme and other natural defense mechanisms are able to clear it.
d. The organism undergoes antigenic shifting and becomes naturally avirulent.
e. None of the above.
The host generates an antibody response by that time and the antibody restricts the organisms to areas that are immunologically privileged.
Which of the following is a soil saprophyte commonly found in decaying wood?
a. Coccidioides immitis
b. Histoplasma capsulatum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Trichophyton equinum
Blastomyces dermatitidis
Which of the following is most commonly found in low-lying areas near reservoirs and dams?
a. Coccidioides immitis
b. Histoplasma capsulatum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Aspergillus flavus
d. Blastomyces dermatitidis
Which of the following has a strong predilection to infect neural tissue?
a. Coccidioides immitis
b. Histoplasma capsulatum variety farciminosum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Sporothrix schenckii
c. Cryptococcus neoformans
Which of the following is has been recovered commonly from rotting portions of trees that are contaminated with feces, insect parts and other debris?
a. Coccidioides immitis
b. Histoplasma capsulatum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Microsporum canis
c. Cryptococcus neoformans
Which of the following is commonly associated with bat feces and bird droppings?
a. Coccidioides immitis
b. Histoplasma capsulatum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Cladosporium species
b. Histoplasma capsulatum
Which of the following has a yeast form that is commonly found in circulating phagocytes of clinically infected hosts. Which of the following is commonly associated with bat feces and bird droppings?
a. Coccidioides immitis
b. Histoplasma capsulatum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Cladosporium species
b. Histoplasma capsulatum
Which of the following is a Biosafety level 3 pathogen transmitted to the respiratory tract by readily aerosolized arthrospores.
a. Coccidioides immitis
b. Histoplasma capsulatum variety farciminosum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Sporothrix schenckii
a. Coccidioides immitis
Which of the following is commonly found on woody plant material and is transmitted by traumatic introduction?
a. Coccidioides immitis
b. Histoplasma capsulatum variety farciminosum
c. Cryptococcus neoformans
d. Blastomyces dermatitidis
e. Sporothrix schenckii
e. Sporothrix schenckii
The major cell type involved in the adverse reaction to endotoxin is:
a. Polymorphonuclear leukocyte
b. Macrophage
c. Eosinophil
d. Mast cell
e. RBC
b. Macrophage
T or F Methicillin-resistant Staphylococcus aureus are not a concern for veterinarians.
false
T or F PCR of the urine has become increasingly available for diagnosis of leptospirosis, especially in the canine species
True
T or F Leptospirosis should be included in the list of differentials if humans develop a febrile illness within one month of being involved in a flood or flood cleanup
True
T or F Recent data indicate that 1/3 of human leptospira infections come from dogs and 1/3 come from rats
True
T or F We commonly vaccinate feeder pigs against Brachyspira hyodysenteriae
False
T or F Intestinal spirochetes are common but very few have been associated with disease.
True
T or F Erythema chronicum migrans is the name of the rash that occurs in about 80% of individuals within the first month following infection with Borrelia burgdorferi
True
T or F Ixodes scapularis is the only species of tick known to reliably transmit Borrelia burgdorferi
False
T or F The human Lyme disease vaccine was pulled off the market and critics claimed that it caused Aodd and damaging side effects@.
True
T or F Many human cases of rat-bite fever are characterized by a chronic relapsing illness with episodes of fever and chills that subside within 36 hours, only to recur in 3 to 9 days.
True
T or F Streptobacillus moniliformis and Spirillum minus are both causes of rat-bite fever.
True
T or F Haverhill fever is similar to rat-bite fever except that GI and respiratory signs are more common and transmission is through ingestion rather than a bite wound.
True
T or F Birds that recover from infections with Chlamydophila psittaci infection can shed the organism in their feces for a very long time and possibly for life.
True
T or F The primary route of transmission for Chlamydophila psittaci in birds is via the respiratory tract by breathing dust contaminated with feces
True
T or F Most cases of Rocky Mountain Spotted Fever are reported from the southeastern region of the U.S.
True
T or F Coxiella burnetii is most commonly transmitted to humans via ticks and is most commonly found in hunters, hikers and others that spend a lot of time outdoors.
False
T or F PCR is the currently recommend method for diagnosis of Potomac Horse Fever.
True
T or F Bovine anaplasmosis can only be transmitted through vectors such as ticks and biting flies
False
T or F The anemia seen in bovine anaplasmosis is due to clearance of RBC=s damaged by infection with the organism and anti-erythrocyte antibody that is generated by the host
True
T or F Complex polysaccharide and protein antigens are T-cell dependent and the immune response is therefore restricted to the IgM isotype of antibody
False
T or F Bacterial antigens that are broken down to antigenic peptides in the phagolysosome of macrophages are said to be exogenously processed
True
T or F An autogenous bacterin is an immunizing product generated from a bacterial isolate obtained from the herd to be immunized
True
T or F Capsule and toxin production in Bacillus anthracis are dependent on the presence of two large plasmids.
True
T or F Pyelonephritis in both cattle and swine usually require some type of predisposing factor.
True
T or F Infection with Nocardia asteroides usually requires some type of predisposing factor such as immunosuppression or traumatic introduction of the organism into tissues.
True
T or F Mycobacterium avium subspecies paratuberculosis can remain viable in soil and feces for up to 9 months
True
T or F E. coli STb toxin is more commonly involved in post-weaning scours in pigs.
True
T or F F18 fimbria are essential for the production of edema disease in swine.
True
T or F Klebsiella pneumoniae is a good recipient for R-factors (antimicrobial resistance genes
True
T or F Bibersteinia trehalosi isolates have the same leukotoxin as Mannheimia haemolytica
True
T or F Respiratory disease in sheep and goats is caused by multiple serotypes of Mannheimia haemolytica whereas disease in cattle is almost always serotype A1
True
T or F Actinobacillus suis and Actinobacillus pleuropneumoniae produce apparently identical Apx1 and Apx2 toxins
True
T or F Haemophilus parasuis is commonly found in the nasopharynx of many normal swine and is transmitted to piglets at a young age
True
T or F Haemophilus parasuis commonly causes disease in young piglets without requiring any predisposing factors or stresses
False
T or F Contagious equine metritis has been eradicated from the U.S.
False
T or F Francisella tularensis biovar tularensis is only found in the Scandinavian countries whereas biovar palaearctica is found in most of the countries in the northern hemisphere
False
T or F So-called Adecending@ tetanus is much more common than Aascending@ tetanus
True
What causes Syphilis in Humans
Treponema pallidum subspecies pallidum
___________ causes Cat scratch disease in ___________
Bartonella henselae
Humans
___________ causes Enzootic abortion in sheep
Chlamydophila abortus
___________ causes conjunctivitis and rhinitis in kittens
Chlamydiophila felis
___________ causes trachoma, (keratoconjunctivitis) in humans
Chlamydia trachomatis biovar 2
___________ causes epidemic typhus in humans
Ricketsia prowazekii
___________ causes ehrlichiosis i, terminal pancytopenia in digs
Ehrlichia canis
___________ causes potomac horse fever in horses
Neorickettsia risticii
___________ causes north american blastomycosis in dogs, humans, and cats
Blastomyces dermatitidis
___________ causes chromomycosis in a wide variety of animals
Curvularia
___________ causes zygomycosis in a wide variety of animals
Mucor
___________ causes club lamb fungus
Trichophyton verrucosum
___________ causes pneumonia in penguins
Aspergillus fumigatus
___________ is the causes of sporothricosis in dogs, humans, horses
Sporothrix schneckii
___________ is the cause of salmon poisoning in digs
Neorickettsia helminthoeca
___________ is the cause of otitis externa (yeast infection) in digs
Malassezia pachydermatis
___________ causes rhinosporidosis in humans
Rhinosporidium
___________ is the cause of oral thrush in humans, birds
Candida albicans
___________ is the cause of cholera in humans
Vibrio cholerae
___________ in the cause of cholera in chickens, turkerys and geese
Pasteurella multocida
___________ is the cause of gastroenteritis in humans
Vibrio parahemolyticus
___________ is the cause of recurrent pyoderma and otitis externa in dogs
Staphylococcus schleiferi
___________ is the cause of strangles in horses
Streptococcus equi
___________ is the cause of pigeon fever in horses
Corynebacterium psuedotuberculosis
___________ is the cause of menigitis in pigs
streptococcus suis
___________ is the cause of diamond skin disease in
Eryosipelothrix rhusiopathiae
___________ is the cause of cervical lymphandenitis in swine
streptococcus porcinus
___________ causes malignant caruncles in humans
Bacillus anthracis
___________ causes food poisoning in humans
Bacillus cereus
___________ is the cause of circling disease in ruminants
Listeria monocytogenes
___________ causes of legionaires disease , pneumonia in humans
Legionella pneumophila
___________ is the cause of contagious metritis in horses
Taylorella equigenitalis
___________ causes polynephritis, cystitis in cattle
Corynebacterium renale
___________ causes polynephritis, cystitis in swine
Actinobaculum swine
___________ causes caseous lymphadenitis in sheep and goats
Corynebacterium pseudotuberculosis
___________ causes a purulent bronchopneumonia and occasional enteritis and arthritis in foals
Rhodococcus equi
___________ causes a severe septicemia in newborn foals
Actinobacillus Equuli
or
E. coli
___________ cuases granulomatous osteomyelitis of the mandible of cattle
Actinomyces bovis
___________ is the causes of tuberculosis in swine
Mycoplasma avium
___________ is the cause of swimming pool granulomas in humans/cold blooded animals
Mycobacterium marinum
___________ is the most common cause of pyometra in dogs
E. coli
___________ causes gram negative mastitis in dairy cattle
E.coli
___________ causes UTI in most species
E. coli
___________ is the cause of bacillary dysentery
Shigella dystenteriae
___________ is the cause of typhoid fever in humans
Salmonella typhi
___________ causes UTIs and otits externa in dogs
Proteus vulgaris
___________ is the cause of scromboid poisoning in humans
Morganella morgani
___________ causes salmonellosis in turkeys
Salmonella arizonae
___________ is the casueof the bubonic plague in humans
Yersina pestus
___________ causes contagious pleuropneumonia in cattle
Mycobacterium mycoides subspecies mycoides SC
___________ is the causes of enteric septicemia in catfish
Edwardseilla ictaluri
___________ is the cause of chronic respiratory disease in chickens
Mycoplasma gallisepticum
___________ causes pinkeye/.keratocnjunctivits in cattke
Moraxella bovis
___________ causes tuberculosis in cattle/bison
Mycobacterium bovis
___________ causes pnuemonia in goats
Mycoplasma capricolum subspecies caprimeumoniae
___________ is the cause of keel disease in ducklings
Salmonella anatum
___________ is the cause of infectious anemia in cats
Mycoplasma haemofelis
___________ causes pullorum disease in chickens/turkeys
Slamonella pullorum
___________ is the cause of chronic respiratory disease in rats
Mycoplasma pulmonis
___________ is the cause of enzootic pneumonia in swine
Mycoplasma hyopneumoniae