Fungi Flashcards
Fungii cell wall
Complex consists of: chitin, glucan, and mannan
Nonseptate Hyphae
- No cross walls
- Broad with irregular width
- Broad angle of branching
Septate Hyphae
Cross walls
Width fairly regular (tube-like)
Key Dimorphic Fungi
- Histoplasma
- Blastomyces
- Coccidioides
- Sporothrix
Body Heat Changes Shape
Dimorphic fungi
Blastomyces
Histoplasma
Coccidioides
Sporothrix
Pt with blotchy hypopigmentation of skin
KOH scraping shows “spaghettie and meatballs”
Malassezia furfur
Trichophyton
Dermatophytes that infect skin, hair and nails
Microsporum
Dermatophytes that infect hair and skin
Epidermophyton
Dermatophytes that infect nails and skin
Pt with subcutaneous/lymphocutaneous mycetoma
Gardener, florist, basket weaver
Cigar-shaped yeasts in pus
Sporothrix schenckii
Histoplasma regions
Eastern Great lakes, Ohio, Mississippi, and Missouri River Beds
Histoplasma found in
Soil enriched with bird or bat feces
What cells is Histoplasma found in
Reticuloendothelial cells
Histoplasma causes
Pneumonia like
Hepatosplenomegaly
Lesions have a tendency to calcify as they heal
Coccidioides region
Southwestern US
Histoplasma tissue form
Small intracellular yeast with narrow neck on bud
NO CAPSULE
Coccidioides tissue form
Spherules with endospores
Valley fever
- Due to Coccidiodes
- Desert bumps (erythema nodosum)
- Arthritis
- Pulmonary lesions have a tendency to calcify
Aspergillus predisposing conditions
Asthma, CF
Fungus ball
Neutropenia, CGD, CF, burns
Cryptococcus source
Soil enriched with pigeon dropping
Pigeon breeder with acute pulmonary symptoms
Cryptococcus
Hodgkins/AIDs pt with meningitis
Cryptococcus
How do you stain Cryptococcus
India Ink
What infection occurs in ketoacidotic diabetic patients and leukemic patients
Mucor
Premature infant or AIDs pt with atypical pneumonia
Pneumocystis
Pneumocystis biopsy reveals
Homneycomb exudate and silver-staining cysts
Xray of Pneumocystis
Ground glass
What does Pneumocystis attach to?
Type 1 pneumocytes causing excess replication of Type 2 pneumocytes
