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Microbiologie > Fungi > Flashcards

Fungi Flashcards

1
Q

Unlike bacteria
Unlike plant
Cell wall

A

Eukaryotic
Lack property of photosynthesis
Chitin

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2
Q

Fungal disease usually…..

A

Chronic

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3
Q

Classification depending on morphology

A

1 yeast unicellular produced by budding
2 mold multicellular filamentous
3 dimorphic fungi mostly pathogenic

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4
Q

Branching cylindrical tubules

A

Hyphe

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5
Q

Mass of interwined hyphe called

A

Mycelium

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6
Q

Hyphe divided into….. And other ….

A

Septate
Non septate

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7
Q

Parasitic form seen in

A

Tissu, exudates, or enriched media at 37
Seen as yeast

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8
Q

In nature or if grown at 25 exis as

A

Mold (mycelia)

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9
Q

Why it’s difficult to make antimycotic therapy

A

Because drugs that inhabit the synthesis of DNA and RNA or protein in fungal may have the same effect on human cells

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10
Q

Fungal cell wall.
Rigid cell wall of…

A

Chitin

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11
Q

Fungal membrane contain……. Where as mammalian cells contain……
This difference is the basic for…

A

Ergosterol
Cholesterol
Fungal sensitivity to intimycotic agent

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12
Q

Asexual spores formed by….

A

Modification of hyphe

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13
Q

Pityriasis versicolore or……. Caused by…….

A

Tinea versicolor
Malassezia furfur mould septate hyphae

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14
Q

Disease of pityriasis versicolor

Infected area recognized by..

A

Dépigmentation of infected skin may be accompanied by itching
By discoloration

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15
Q

Diagnosis of
Pityriasis versicolor
Tinea versicolor

A

Microscopic examination koh
Treated skin scraping

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16
Q

The lesion of pityriasis versicolor appear fluorescence yellow orange under…….. Lesion found in……

A

Wood light
Trunk and arms

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17
Q

Tenia Nigra….

A

Brown to black macular lesion usually on the hands and feet and the causative agent fungus found in soil and environment

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18
Q

Piedra is infection of……. Caused by…….. And……….

A

Scalp hair
Piedraia hortae and Trichosporon Beigelii

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19
Q

p.hortae is a dark pigmented……. cause….., Small brown black modules are formed on……..
Dark coloured thick…….

A

Mould
Black piedra
Hair surface
Hyphae

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20
Q

Trichosporon Beigelii is not…… Infect………. Causing…….
White nodules are formed having………

A

Dark coloured
Course of hair (axillary, facial, genital)
White piedra
No pigmented hyphae

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21
Q

Diagnosis of peidra

A

Microscopic examination koh
p.hortea show dark coloured branching thick septete hyphae+Ascospores sexal
Trichosporon Beigelii show soft white or pale brown hyphae+arthrospores

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22
Q

Another name of cutaneous mycosis

A

Dermatophytosis
Ring worm
Tinea

23
Q

Ring worm affect……

A

Keratinized tissue of nails and hair and skin

24
Q

…. Infect skin and hair and nails
….infect skin and hair not nails
….infect skin and nails

A

Trichophyton Rubrum
Microsporum
M.canis

25
Q

Tenea corporis

A

Ring worm occur any where on the body

26
Q

Tinea pedis

A

Athletes foot
Toe webs and sole of feets

27
Q

Tinea unguium

A

Onchomycosis
Infections of nails

28
Q

Tinea manuum

A

Infections of hands

29
Q

Tinea capitis

A

Affect scalp of children transmitted by comb in school going children

30
Q

Tinea cruris

A

Jock itch
Infections of groin, perineum, perianal

31
Q

Tinea barbae

A

Ring worm of bearded area on face

32
Q

Skin ring worm common in ……

A

Moist sweaty skin folds
Obisity increase susceptibility to infection beneath breast and tight clothes help infection in groin

33
Q

Maceration and moisture help setting infections between……

A

Toes (athletes foot)

34
Q

Lab diagnosis of tinea

A

Skin scraped from advancing edge (septete hyphae)
Dermatophytes fluoresce seen under u.v light (wood lamp)

35
Q

Treatment of ring worm
Tinea

A

Topical therapy
Tolneftate,Naftifne,clotrimazole.miconazole
Oral therapy griseofulvin or ketoconazole or allylamine (nails bed infections)

36
Q

Subcutaneous mycosis

A

Introduced by injury through the skin
Involved subcutaneous tissue،lymphatic tissue, and nearby tissue
Rarely spread to distan organ

37
Q

Etiology of sporotrichosis

A

Sporothrix schenckii
Dimorphic fungi
Cigar shaped yeast in tissue

38
Q

Sporothrix schenckii is……. found in soil in decaying organic matter. Acquired by….

A

Ubiquitous saprophytes
Traumatic inoculation through skin of
Gardeners, farmers

39
Q

Pathology of sporothrix schenckii

A

Pyogenic and granulomatous inflammation

40
Q

Skin lesions of sporothrix schenckii begin as……
……. Is most often involved
…… Later………..

A

Painless papule
Hand
Papule
Ulcerate, draining lymph channels thickened or firm nodules

41
Q

Diagnosis of Sporothrix schenckii

A

Specimens
Direct microscopic examination
Culture sda,bhia

42
Q

In sporothrix schenckii
Koh preparation usually…….. Due to…..

A

Negative
Small number of fungi

43
Q

Asteroid bodies in the lesion of……

A

Sporothrix schenckii
Is central fungus cell surrounded by refractile esinophilic halo called
Splendor hoeppli phenomenon due to complex deposition around the organisms

44
Q

Culture of sporothrix schenckii

A

Septate hyphae
Very thin carry flower like cluster of small conidia

45
Q

Treatment of sporothrix schenckii

A

Itraconazole
Sever amphotericin B

46
Q

Chromoblastomycosis?

A

Chronic warty mycosis of the skin and subcutaneous tissue cused by Phialophora and cladosporium genera which are pigment producing filamentous fungi

47
Q

Chromoblastomycosis occur in…..or….. Appear as….. that develop after several years into………
Extension is…. And…… And doesn’t involve…..

A

Foot or legs
Papule
Flat scaly or warty like structure under the feet like tips of Cauliflower
Slow
Painless
Lymphatic vessels

48
Q

Lab diagnosis of chromoblastomycosis depending on…

A

Culture and isolation

49
Q

In chromoblastomycosis
Diagnosis
Organisms are called……….. Fungi because they grow as………
The pigment accumulates in the mycelia cell wall in culture and in tissue……

A

Dematiaceous
Black colonies
Sclerotic bodies

50
Q

Treatment of chromoblastomycosis

A

Surgery and antifungal therapy
Itraconazole , amphotericin B and fluorocytosine

51
Q

Mycetoma is……..
It characterised by………
It’s typically affect the………..
Predominantly occur in……

A

Chronic granulomatous disease of the skin and subcutaneous tissue which sometimes involve muscle bone and neighboring organ
Tumefaction, abscess formation, and fistulae
Lower extremities
Farm workers

52
Q

Mycetoma swelling is ….. And contain……
…… Containing small granules….
Is discharge through….. Which opens on the skin surface

A

Nodular
Sinuses
Mucopus
Colonies
Sinuses

53
Q

Diagnosis of mycetoma

A

Specimens exudates from sinuses And biopsy from granules
Culture

54
Q

Treatment of mycetoma

A

Surgical excision
Ketoconazole 1,3 years
Actinomycetes mycetoma respond to antibiotics and sulphonamide

Microbiologie (16 decks)

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