Fundamentals of Histology Flashcards

1
Q

What are neutrophils associated with

A

Acute inflammation

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2
Q

What are lymphocytes and plasma cells associated with

A

Chronic inflammation (lymphomas)

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3
Q

What are eosinophils associated with (3)

A

Allergic reactions.
Parasitic infections.
Tumours (e.g. Hodgkin’s disease)

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4
Q

What are macrophages associated with (2)

A
Late acute inflammation. 
Chronic inflammation (including granulomas)
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5
Q

Name a few types of tumours (3)

A

Carcinoma.
Sarcoma.
Melanoma.

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6
Q

What are the histological characteristics of squamous cell carcinomas (2)

A

Keratin production.

Inercellular bridges.

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7
Q

What are the histological characteristics of adenocarcinomas

A

Mucin producing glands

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8
Q

What are some sites of origin of squamous cancers (6)

A
Skin 
Head and neck. 
Oesophagus. 
Anus. 
Cervix. 
Vagina.
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9
Q

What stain can be used to stain for glandular epithelium

A

Mucin stain

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10
Q

What are some sites of origin of adenocarcinomas (5)

A
Lung. 
Breast. 
Stomach. 
Colon. 
Pancreas.
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11
Q

What stain is used to detect melanoma

A

Fontana stain

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12
Q

What are the two types of stain (2)

A

(Histo)chemical

Immunohistochemical

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13
Q

What are histochemical stains based on (2)

A

Based on the chemical reaction between the stain and a specific component of the tissue.
The product of this reaction has a specific colour or other property which can be identified.

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14
Q

What stain is used to detect haemochromatisis

A

Prussian blue stains iron stain positive

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15
Q

What stain is used to detect amyloid

A

Congo red positive

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16
Q

What are immunohistochemical stains based on (2)

A

Based on using an antibody specific to an antigen in the tissue
Need a detection system to make this binding visible

17
Q

What is an epithelial marker

A

Cytokeratin

18
Q

What is a lymphoid marker

A

CD45