Brief Lipid Update

Question 1

What is the best management approach for patients with high blood pressure

Answer 1

Aggressive management of blood pressure and lipids improves survival

Question 2

What is PCSK9 therapy

Answer 2

Useful in patients with known CVD to lower blood lipids and safely reduce major cardiovascular events when added to statin therapy

Question 3

Who is PCSK9 therapy reserved for

Answer 3

High risk patients: statin intolerant, uncontrolled lipids (e.g. FH), high net value patients.

Question 4

What is the preferred initial pharmacological agent for the treatment of T2DM

Answer 4

Metformin

If non-insulin monotherapy at maximum tolerated doses not work after 3 months, add a second oral agent, a GLP-1 receptor agonist, or basal insulin.

In patients with long-standing suboptimally controlled T2DM and established CVD, empagliflozin or liraglutide should be considered