FUCK I FORGOT I NEEDED TO KNOW THIS Flashcards
define a monoclonal antibody
identical copies of one type of antibody
what are antibodies and what are they produced by?
-proteins
-lymphocytes
how does the body recognise and attack pathogens?
-the lymphocytes recognise the antigens on pathogens as foreign and produce antibodies to attack them
what did scientists discover about antibodies?
-can make antibodies to bind to antigens on other substances, not just pathogens
-once bound, these are merged tightly together, making them easier to identify
describe the formation of monoclonal antibodies
-antigen injected into a mouse
-mouse produces lymphocytes, which produce antibodies specific to the antigen that was injected
-lymphocytes removed from the mouse
-spleen cells fused with human cancerous white blood cells called meloma cells to form hybridoma cells which divide indefinitely
-hybridoma cells divide and produce millions of monoclonal antibodies specific to the original antigen
which type of cell produces lymphocytes?
spleen cells
name 3 uses of monoclonal antibodies
-pregnancy tests
-cancer diagnosis
-cancer treatment
how do pregnancy test kits use monoclonal antibodies
-monoclonal antibodies designed to bind with hCG, which is only found in the pee of pregnant women
-if hCG is present, the monoclonal antibodies will stick to it and a colour change will happen
how do cancer diagnosis’s use monoclonal antibodies
-bind to antigens on cancer cells and mark them to make them easy to find
what is a keystone species?
-one that plays a specific role within the ecosystem
what is an indicator species for clean water?
mayfly larva
what is an indicator species for a bit of water pollution?
-freshwater shrimp
what is an indicator species for a moderate level of water pollution?
bloodworm
what is an indicator species for a high level of water pollution?
red-tailed maggot
what is an indicator species for clean air?
bushy lichens
what is an indicator species for slightly polluted air?
leafy lichens
what is an indicator species for very polluted air?
crusty lichens
what are the cells that help provide energy for the sieve tubes called?
companion cells