Frontotemporal Dementia

Question 1

The three core clinical syndromes of FTD are ?

Answer 1

behavioral variant (bvFTD)
semantic variant 
nonfluent/ agrammatic variant

Question 2

Any of the three core clinical syndromes,but most often bvFTD may be accompanied by ?

Answer 2

Motor Neuron Disease

Question 3

Neuronal and glial inclusions in patients with FTD contain ?

Answer 3

tau or TDP-43 in 90% of patients and FUS in 10%

Question 4

Which brain areas are mainly invovled on Progressive Supranuclear Palsy ?

Answer 4

Brainstem,Basal Ganglia, Diencephalon and selected areas of the cortex

Question 5

Prominent features of PSP ?

Answer 5

Dysarthria, dysphagia and symmetric axial rigidity (frequent unxeplained falls are common)

Question 6

Typical presentations of Corticobasal Syndrome ?

Answer 6

Asymmetric onest of rigidity,dystonia, myoclonus, apraxia of one limb,at times associated with alien limb phenomena