Free 120 Flashcards

1
Q

Type 2 pneumocytes function

A

Secrete surfactant
Serve as stem cells to make type I and type 2 cells

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2
Q

Sarcoidosis pathophysiology

A

Granulomatous disorder that effects calcium homeostasis due to overactivation of macrophages and increased renal production of vitamin D

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3
Q

Are there noncaseating or caseating granulomas in sarcoidosis?

A

Non-caseating granulomas, widespread

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4
Q

Pheochromocytomas are found in MEN1 or MEN2

A

MEN 2

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5
Q

RET is a tumor suppressor or protooncogene

A

protooncogene
Its a receptor tyrosine kinase
Think growth

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6
Q

MEN1 mutation (menin, chromosome 11) is a tumor suppressor or protooncogene

A

tumor suppressor (2 hit)

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7
Q

Medullary thyroid cancer is neoplasm of what kind of cells?

A

parafollicular - calcitonin

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8
Q

Fremitus is increased in what situation

A

When there is consolidation like a lobar pneumonia

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9
Q

Function of leptin

A

Satiety, decreases appetite

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10
Q

Obese people have increased or decreased leptin

A

Increased because leptin is secreted by adipose tissue

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11
Q

Describe Type I error

A

Stating that there is a difference when none exists

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12
Q

Describe type II error

A

Stating there is not a difference when there is

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13
Q

Bronchiectasis is obstructive or restrictive

A

Obstructive
Chronic cough and daily sputum production

Associated with cystic fibrosis

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14
Q

Rifampin changes warfarin metabolism in what way?

A

It is a CYP450 inducer = warfarin gets metabolized more quickly and it doesn’t work as well = low INR

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15
Q

Which lab technique is best for detecting viral RNA/DNA

A

Reverse transcription PCR0

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16
Q

Which antibiotic class is best used for pertussis?

A

Macrolides

17
Q

Method of action of terbinafine (tinea pedis treatment)

A

Inhibition of squalene monooxygenase which disrupts ergosterol synthesis (fungal cell membranes)

18
Q

Opening pressure is increased in bacterial, fungal, or viral meningitis

A

All but viral is closer to normal

19
Q

Glucose is low in bacterial, fungal, or viral meningitis?

A

Bacterial and fungal.
It is normal in viral

20
Q

Compare hemidesmosomes and desomosomes

A

Desmosomes connect cells side to side

Hemidesmosomes connect cells to the basement membrane

21
Q

Autoantibodies to desmosomes result in what skin condition

A

Pemphigus vulgaris