*Found Concept: MEDICATION ADMINISTRATION Flashcards
Pharmacokinetics
study of absorption distribution metabolism excretion of medication
absorption
how it gets in body
metabolism
how its broken down
Excretion
how it leaves the body
Ionization
The pH of the medication and the site of absorption
Dissolution
medication dissolves before absorption can take place
Highly lipid soluble
absorbed rapidly
Enteral route
medication administered via the mouth stomach or intestine
toxicity
an adverse effect in which the body is unable to metabolize or excrete medication
Prodrugs
are inactive chemicals that are activated through metabolism to exert their therapeutic effects
Therapeutic effect
the desired effects of a medication
first pass effect
the passage of oral medication from Small intestine to the hepatic circulation via the mesenteric and portal veins flowing into the liver before reaching systemic circulation
Pharmacodynamics
Study on how medicine works
Therapeutic drug monitoring TDM
monitor medication concentration in a clients blood
Peak blood level
when a medication is at its highest concentration
trough blood level
is the lowest level of concentration of a medication
Half life
time it takes for the medication to fall half its strength through execration
Adverse drug reaction ADR
unintended and nontherapeutic effects which can be tolerable to harmful
iatrogenic
unforeseeable or unintended physical condition, injury or disorder caused by treatment or procedure
Anaphylaxis
life threatening reaction in which the immune response produces dyspnea, hypotension, tachycardia
drug-drug interaction
occur anytime a client is prescribed more than one medication
drug-food interaction
can also impact rate of absorption by delaying it or enhance it
teratogenic
medication that can cause fetal defects, pregnancy loss, prematurity or developmental disabilities
Polypharmacy
multiple medication that one person takes
MAR medication administration record
record of medication
time critical medication
must be given within 30 min before or after scheduled time
buccal
is medication given between the cheek and the gum
Intramuscular
into the muscle.
subcutaneous
beneath the skin
transdermal
applied to the skin
Enteric coated
medication that dissolves in small intestine for a slower release and given less frequently in a day
Sustained release
tablet designed to release medication slowly over an extended period of time
transdermal
delivery absorbed by the skin
ophthalmic
pertaining to eye
otic
pertain to ear
5cc is the same as 5mL
yes
needle size
the bigger the number the thinner the needle
intramuscular angle degree?
90*
subcutaneous angle degree
45-90*
intradermal injection angle degree
5-15*
Intramuscular route
delivered into a large skeletal muscle. faster rate of absorption. large medication amount
Aspiration
when the content of the stomach move into the lungs
Dorsogluteal
located on the butt
ventro-gluteal
between the iliac crest and the anterior superior iliac spine (side of upper thigh)
deltoid
below the acromion process. (upper arm)
vastus lateralis
Anterior lateral aspect of the thigh. middle side of thigh
PICC
for short term IV therapy. lies in the superior vena cava at the entrance of the right atrium insert through arm
CVC
insert through chest directly into large vein.
phlebitis
inflammation of the vein
inflitration
occurs when an infusing intravenous fluid or medication goes to surrounding tissue.
four components of pharmacokinetics
- absorption
- distribution
- metabolism
- excretion
high alert medication
medication that can harm the patient if given the wrong dose. medication must be verified by 2 nurses. ex: insulin, opiates, heparin, potassium chloride